Coronavirus (COVID-19) Q&A

Rural Maternity Care Is in Crisis—Here’s What Could Help; Type and Severity of Immunodeficiency Affect Speed of SARS-CoV-2 Clearance, Study Finds Related Content:

Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. Related Content:

The COVID-19 pandemic has caused major disruptions in ambulatory care. In this interview with JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses how access to care and preventive services changed for different racial and ethnic groups in the US from 2019 to 2022. Related Content:

Two recent studies find that COVID-19 vaccination during pregnancy is safe for infants and effective for children aged 1-4 years. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, and JAMA Pediatrics Associate Editor Alison Galbraith, MD, discuss clinical and policy implications with Grace Lee, MD, MPH, professor of Pediatrics at Stanford University School of Medicine, Palo Alto, California. Related Content:

During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. Related Content:

Interview with Jay F. Piccirillo, MD, author of Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Related Content:

In this interview, JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, explore with Erin K. McCreary, PharmD, and Atheendar S. Venkataramani, MD, PhD, how a large regional health system used a weighted lottery and intensive outreach to provide high-risk individuals in disadvantaged communities more equitable access to scarce monoclonal antibodies for preventing COVID-19. Related Content:

JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, discuss with Sandra B. Nelson, MD (Massachusetts General Hospital, Boston), her JAMA Health Forum study of transmission of SARS-CoV-2 in schools in Massachusetts during 2 different phases of the COVID-19 pandemic. She found transmission rates were very low but varied by district and the availability of vaccines. Related Content:

Interview with Rishi P. Singh, MD, author of Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data. Hosted by Neil Bressler, MD. Related Content:

The COVID-19 pandemic has disrupted health care in many domains, including mental health services. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Ryan K. McBain, PhD, MPH, of RAND Corporation how the use of mental health care—both in-person and telehealth visits—changed for commercially insured adults during the first year of the COVID-19 pandemic in 2020.

Interview with Matthew S. Durstenfeld, MD, MAS, and Priscilla Y. Hsue, MD, authors of Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis. Hosted by Angel N. Desai, MD, MPH. Related Content:

In July 2022, Nahid Bhadelia, MD, MALD, joined the White House COVID-19 Response Team as senior policy advisor for Global COVID Response. The infectious disease physician, who is on sabbatical from Boston University, spoke with JAMA Associate Managing News Editor Jennifer Abbasi about the pandemic’s true burden of disease in low- and middle-income countries and ongoing COVID-19 vaccine inequity.

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Early in the COVID-19 pandemic, most states approved temporary regulatory changes so out-of-state physicians could provide telemedicine services to residents. Ateev Mehrotra, MD, of Harvard Medical School, and Chad Ellimoottil, MD, MS, of the University of Michigan, speak with JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, about the features of telemedicine visits provided for Medicare beneficiaries across state borders during the first year of the pandemic and potential policy changes that would enable such visits to continue.   Related Content:

On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022.

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Interview with Elizabeth M. Harry, author of Childcare Stress, Burnout, and Intent to Reduce Hours or Leave the Job During the COVID-19 Pandemic Among US Health Care Workers.Hosted by Angel N. Desai, MD, MPH.

Interview with Paolo Boffetta, MD, author of Global Association of COVID-19 Pandemic Measures With Cancer Screening: A Systematic Review and Meta-analysis. Hosted by Jack West, MD.

What a Post–Roe v Wade US Might Look Like for Physicians; SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus

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As the White House’s COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government’s continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19.

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Interview with Peter Watkinson, MD, and Julia Hippisley-Cox, MD, authors of Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections. Hosted by John Torous, MD, MBI.

The health care workforce has yet to recover from the COVID-19 pandemic, and there is a concerning trend of increasing numbers of physicians leaving the workforce. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Bianca Frogner, PhD, of the University of Washington new findings that show how all segments of the health care workforce have struggled, with more pronounced effects among long-term care workers, aides, assistants, workers with young children, and workers of color.

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Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast.

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Reducing “COVID-19 Misinformation” While Preserving Free Speech

Interview with Cheng-Ying Ho, MD, PhD, author of Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19. Hosted by Cynthia E. Armand, MD.

Interview with Michael Springer, PhD, and Andrew Bo Liu, authors of Association of COVID-19 Quarantine Duration and Postquarantine Transmission Risk in 4 University Cohorts Hosted by Angel N. Desai, MD, MPH.

Interview with Ilana Doweck, MD, author of Association Between the BNT162b2 Messenger RNA COVID-19 Vaccine and the Risk of Sudden Sensorineural Hearing Loss, and Eric J. Formeister, MD, MS, author of Assessment of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination Hosted by Joseph P. Bradley, MD.

Pregnant and recently pregnant individuals who become infected with the COVID-19 virus are at high risk of requiring extra medical care. JAMA Associate Editor Linda Brubaker, MD, MS, from University of California San Diego discusses the rapidly evolving data around COVID-19 and vaccine effectiveness and safety as it relates to pregnancy, breastfeeding, and fertility with 3 experts in the field: Laura E. Riley, MD, from Weill Cornell Medicine, Christina Chambers, PhD, MPH, from University of California San Diego School of Medicine-Pediatrics, and Denise Jamieson, MD, MPH, from Emory University.

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Conflict of Interest Disclosures:

Dr Chambers reported receiving research funding from Pfizer-BioNTech to study the safety of its COVID-19 vaccine in pregnancy.

Dr Jamieson reported no disclosures.

Dr Riley reported receiving compensation from UpToDate for work on several infections disease cards, receiving royalties from Turner Publishing, and serving on an advisory board for Maven. Dr Riley also reported serving on a CDC Advisory Committee on Immunization Practices workgroup on COVID-19 vaccines and vaccine safety and workgroups for the American College of Obstetricians and Gynecologists and Society for Maternal-Fetal Medicine of COVID-19 vaccination, without compensation.

For the duration of the COVID-19 pandemic public health emergency, state Medicaid programs elected to maintain eligibility for Medicaid recipients in exchange for increased federal funding. In this podcast, Dr Laura Dague of the Bush School of Government & Public Service at Texas A&M University discusses her JAMA Health Forum article finding that this policy was associated with the higher Medicaid enrollment seen during the pandemic. JAMA Health Forum Editor John Ayanian and Deputy Editor Melinda Buntin discuss the policy implications of this work with Dr Dague and other recent articles touching on Medicaid enrollment.

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Trends in Medicaid Enrollment and Disenrollment Early in the COVID-19 Pandemic in Wisconsin

Medicaid Disenrollment After the COVID-19 Pandemic

Medicaid Coverage Disruptions Among Children Enrolled in North Carolina Medicaid, 2016-2018

Association of Medicaid Expansion in Arkansas With Postpartum Coverage, Outpatient Care, and Racial Disparities

Interview with Steven Woloshin, MD, MS, author of At-Home Self-Testing Kits for SARS-CoV-2: A Randomized Trial Assessing How Consumers Interpret and Act on Possible Test Results. Hosted by Deborah Grady, MD, MPH.

Interview with Walter S. Gilliam, PhD, and Thomas S. Murray, MD, PhD, authors of Association of Child Masking With COVID-19–Related Closures in US Childcare Programs. Hosted by Angel Desai, MD.

Three members of President Biden’s former COVID-19 Advisory Board—Luciana Borio, MD, Ezekiel Emanuel, MD, PhD, and Mike Osterholm, PhD—discuss their recent JAMA Viewpoints, providing their ideas on strategies for public health as COVID-19 transitions from pandemic to endemic. Hosted by JAMA Associate Editor Preeti Malani, MD.

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Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022.

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Infectious disease experts Adam Lauring, MD, PhD, and Carlos del Rio, MD, join JAMA Associate Editor Preeti Malani, MD, MSJ, for a discussion of the newly emerged Omicron variant, the potential for a 2021-2022 "twindemic" with flu, and the latest COVID-19 clinical updates. Recorded December 1, 2021.

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Interview with Cédric Lemogne, MD, PhD, and Joane Matta, PhD, authors of Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic. Hosted by Mitchell H. Katz, MD.

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COVID-19 Crisis Advances Efforts to Reimagine Nursing Homes; Moving COVID-19 Testing Out of the Clinic and Into the Home; The Lingua Franca of Addiction—Stigmatizing Words That Wound

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Interview with Alex C. Spyropoulos, author of Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial

The longstanding shortcomings of the US nursing home model became more visible during the COVID-19 crisis. Terry Fulmer, PhD, RN, a geriatric nurse practitioner and president of the John A. Hartford Foundation in New York City, discusses the challenges skilled nursing facilities face and shares her vision for nursing homes that better serve residents and support the workforce.

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Canadian law gives the country’s individual provinces and territories primary responsibility for coronavirus containment and mitigation. JAMA Associate Editor Preeti Malani, MD, MSJ, from the University of Michigan and Allan S. Detsky, MD, PhD, from the University of Toronto, Ontario, Canada, discuss the national pandemic experience, including public health responses to infection and vaccine allocation, from fall 2020 through summer 2021.

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Interview with Grayson W. Armstrong, MD, MPH, author of Association of Patient Characteristics With Delivery of Ophthalmic Telemedicine During the COVID-19 Pandemic, and Fasika Ambachew Woreta, MD, MPH, author of Analysis of Sex Diversity Trends Among Ophthalmology Match Applicants, Residents, and Clinical Faculty

Ngozi O. Ezike, MD, director of the Illinois Department of Public Health, discusses state and regional management of the COVID-19 pandemic. Recorded November 9, 2020.

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Universal Masking in the United States

Many patients experience neurocognitive deficits, PTSD, and generalized weakness and disability following an intensive care unit (ICU) stay. JAMA Medical News Senior Writer Rita Rubin talks with E. Wesley Ely, MD, MPH, a professor of medicine at Vanderbilt University School of Medicine, about ICU aftereffects, post-acute COVID-19 syndrome, and how the coronavirus pandemic, particularly hospitals’ restrictions on visitors, impeded progress made since the 1990s in caring for the critically ill.

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How COVID-19 Made It Even Tougher to Know ICU Patients as Individuals

We know that the pandemic caused millions of people to lose their jobs, and potentially their job-based insurance, and yet new survey data showed surprisingly small changes in uninsurance rates at the end of 2020. Kate Bundorf, PhD, from the Sanford School of Public Policy at Duke University and Jessica Banthin, PhD, of the Urban Institute talk to JAMA Health Forum Deputy Editor Melinda Buntin about these trends and the role played by Medicaid and exchange coverage. JAMA Health Forum Editor John Ayanian and Melinda Buntin also discuss other recent work about health insurance coverage and the ACA that has appeared in JAMA Health Forum.

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Interview with Alexander T. Hillel, M.D., author of Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care

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The COVID-19 pandemic has had far-reaching effects on the use of health care services. Dr Nora Becker of the University of Michigan talks about her research on reductions in the use of women’s preventive health services, and JAMA Health Forum Editors Dr John Ayanian and Dr Melinda Buntin discuss other JAMA Health Forum pieces on the effects of state “reopenings” on COVID-19 hospitalizations and deaths, the effects of day care closures on women’s participation in the labor force, and news about nursing home outbreaks of COVID-19.

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Lung transplantation has become an option of last resort for a small subset of patients with COVID-19-related acute respiratory distress syndrome (ARDS) or pulmonary fibrosis. Ankit Bharat, MD, chief of Thoracic Surgery and director of Lung Transplant and ECMO at Northwestern Memorial Hospital in Chicago, discusses his experience performing lung transplants for patients with respiratory failure due to COVID-19, including the first successful double lung transplant in the US for a patient with COVID-19-related ARDS.

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Lung Transplants for COVID-19—The Option of Last Resort

Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants; An Inside Look at a Post–COVID-19 Clinic; COVID-19 and the “Lost Year” for Smokers Trying to Quit

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COVID-19 leaves some people with a troubling constellation of symptoms that has been known as long-haul COVID but now has a more formal name: postacute sequelae of SARS-CoV-2 infection (PASC). Currently, 33 states in the US have at least 1 clinic dedicated to caring for patients with PASC. Aluko Hope, MD, a pulmonary and critical care physician, cofounded the Montefiore-Einstein COVID-19 Recovery Clinic in New York in 2020. Now the medical director of the Long Covid-19 Program at the Oregon Health & Sciences University, Dr Hope provides insight into the care provided at a post-COVID-19 clinic.

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An Inside Look at a Post–COVID-19 Clinic

Roberta L. Schwartz, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among asymptomatic health care workers and community residents in the greater Houston, Texas, area.

Read the article here: https://ja.ma/3f8lvcz.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

US Food and Drug Administration (FDA) Commissioner Stephen Hahn, MD, discusses the agency's role in responding to the COVID-19 pandemic. Recorded July 30, 2020.

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Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)

Katherine Auger, MD, MSc, of Cincinnati Children's Hospital and Julie Donohue, PhD, of University of Pittsburgh's Graduate School of Public Health discuss K-12 school reopening policy options and the way forward for the 2020-21 school year. Recorded July 29, 2020.

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Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

Ford Foundation President Darren Walker discusses the role of philanthropic organizations in responding to the COVID-19 pandemic and to health inequities. Recorded July 28, 2020.

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The Work of Philanthropy in Responding to COVID-19 and Addressing Inequality

David N. Fisman, MD, MPH joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines the trends and risk factors associated with coronavirus disease 2019 (COVID-19) death in long-term care facilities in Ontario, Canada.

Read the article here: https://ja.ma/39oLDyy.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Eric Topol, MD, Scripps Research EVP and omnivorous science health care and tech commentator, discusses the evolving COVID-19 pandemic. Recorded July 23, 2020.

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Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers

Catherine L. Auriemma, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines changes in completion of and expressed preferences on an online advanced directive platform during the coronavirus 2019 (COVID-19) pandemic. Read the article here: https://ja.ma/39gbXLe.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Both remdesivir and dexamethasone have been promoted as effective treatments for COVID-19. JAMA Deputy Editor Greg Curfman, MD, and Professor Rachel Sachs, JD, from the Washington University School of Law discuss the science and health policy aspects of these COVID-19 treatments.

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Missed Opportunities on Emergency Remdesivir Use

CDC Director Robert R. Redfield, MD, discusses the ongoing COVID-19 pandemic and the agency’s latest recommendations. Recorded July 14, 2020.

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Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now

Kalpalatha K. Guntupalli, MD, of Baylor College of Medicine discusses the surge and ICU management of COVID-19 patients in Houston, Texas. Recorded July 10, 2020.

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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Ramez Kouzy, MD, Joseph Abi Jaoude, MD, and Ethan Ludmir, MD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a systematic review examining current randomized clinical trials of therapeutic agents to treat coronavirus disease 2019 (COVID-19).

Read the article here: https://ja.ma/2B21PJs.

Whether the SARS-CoV-2 virus is transmitted by droplets or aerosol influences which public health interventions might slow its spread. Michael Klompas, MD, professor of medicine at Harvard Medical School, explains evidence to date about mechanisms of coronavirus transmission and implications for pandemic containment and mitigation efforts.

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Airborne Transmission of SARS-CoV-2: Theoretical Considerations and Available Evidence

Infectious disease physician Rochelle P. Walensky, MD, of Harvard University discusses the ongoing COVID-19 pandemic. Recorded July 8, 2020.

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Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

Anthony Fauci, MD, White House Coronavirus Task Force member and Director of the National Institutes of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded on July 2, 2020.

Interview with Daniel M. Weinberger, PhD, author of Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses latest developments in the COVID-19 pandemic. Recorded on June 29, 2020.

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Interpreting Diagnostic Tests for SARS-CoV-2

Intensivists Flavia R. Machado, MD, PhD, of the Federal University of São Paulo, and Jorge Salluh, MD, PhD, of the D’OR Institute for Research and Education in Rio de Janeiro, discuss the surge of COVID-19 cases and ICU management of patients in Brazil. Recorded June 26, 2020.

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Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit

Alhaji Cherif, PhD and Peter Kotanko, MD join JAMA Network Open Editors to discuss a study examining the feasibility of using pool testing to identify patients with coronavirus disease 2019 (COVID-19) in a setting with limited testing availability.

Read the article here: https://ja.ma/3e8OCvJ

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Chicago public health legend and retired physician Linda Rae Murray, MD, discusses systemic racism and the pandemic’s disproportionate effect among African Americans and other people of color with JAMA Medical News Associate Managing Editor Jennifer Abbasi. Dr Murray is an adjunct assistant professor at the University of Illinois at Chicago School of Public Health and a past president of the American Public Health Association.

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Taking a Closer Look at COVID-19, Health Inequities, and Racism

Michael Osterholm, PhD, MPH, of UMN's Center for Infectious Disease Research and Policy, discusses the summer rise in US COVID-19 cases, prospects for school reopening, a "second wave" in the fall, and more. Recorded June 24, 2020.

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Vulnerability to Pandemic Flu Could Be Greater Today Than a Century Ago

Gina M. Piscitello, MD joins JAMA Network Open Editors to discuss a systematic review that examines US state guidelines for ventilator allocation decision-making during the coronavirus disease 2019 pandemic. Read the article here: https://ja.ma/2YpfVxf.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Fabio Ferreli, MD, and Giuseppe Mercante, MD, authors of Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019

Infectious disease and global health expert Carlos del Rio, MD, of Emory University provides an update on the status of the #COVID19 pandemic in summer 2020, prospects for effective treatment and prevention, communicating the ongoing risk to the public, and more. Recorded June 15, 2020.

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Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response

COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020.

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Management of COVID-19 Respiratory Distress

Joseph M. Unger, PhD joins JAMA Network Open Editors to discuss a cohort study investigating how the coronavirus disease 2019 (COVID-19) pandemic is associated with national enrollment in cancer clinical trials.

Read the article here: https://ja.ma/2MNv1Gs.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Jay Shore, MD, MPH, author of Telepsychiatry and the Coronavirus Disease 2019 Pandemic—Current and Future Outcomes of the Rapid Virtualization of Psychiatric Care

Joshua M. Sharfstein, MD, and Christopher Morphew, PhD, of Johns Hopkins University discuss options for opening primary, middle, and high schools in fall 2020. Recorded June 3, 2020.

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The Urgency and Challenge of Opening K-12 Schools in the Fall of 2020

NIAID Director Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor in Chief Howard Bauchner, MD. Recorded June 2, 2020.

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Anthony Fauci, MD, on COVID-19 Vaccines, Larry Kramer, and Dealing With Criticism

Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020.

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Interview with Brit Trogen, MD, MS, author of Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust

Tristan Morichau-Beauchant, MD joins JAMA Network Open Editors to discuss a case series that reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit in France with severe coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/307784k.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Paul Starr, PhD, Professor of Sociology and Public Affairs at Princeton University, discusses policy options for achieving a new normal in the COVID-19 pandemic. Recorded Thursday, May 28, 2020.

Related Article: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic

US National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, discusses the agency's new initiative to collaborate with other agencies and industry to accelerate development and testing of COVID-19 treatments and vaccines. Recorded May 19, 2020.

Related: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecedented Partnership for Unprecedented Times

The University of New Mexico's Eileen Barrett, MD, MPH, speaks with JAMA's Jennifer Abbasi about the pandemic's mental and emotional toll on health care workers—and how they and their employers can safeguard their well-being.

Read the article: Prioritizing Physician Mental Health as COVID-19 Marches On

Was the stay-at-home order in Illinois associated with different rates of coronavirus disease 2019 (COVID-19) compared with Iowa, which did not issue a stay-at-home order? Wei Lyu, MS and George L. Wehby, PhD join JAMA Network Open Editors to discuss a cross-sectional study comparing coronavirus disease 2019 (COVID-19) cases in border counties in Iowa and Illinois to find out if issuing a stay-at-home order helped limit the spread of COVID-19 cases. Read the article here: https://ja.ma/2LNprmO.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Ezekiel Emanuel, MD, PhD, of the Perelman School of Medicine's Department of Medical Ethics and Health Policy, discusses the use of immunity licensing (immunity passports) as a means to restore public travel, activity, and the economy following the first wave of the COVID-19 pandemic. Recorded May 11, 2020.

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The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

Ruoran Li, MPhil joins JAMA Network editors to discuss a comparative effectiveness study describing and comparing the intensive care unit and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak number of intensive care unit beds needed in US cities if an outbreak equivalent to that in Wuhan occurs. Read the article here: https://ja.ma/3cySE0m.  

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Preprint servers and professional discourse on social media sites like Twitter have been incredibly helpful in spreading useful information as the COVID-19 pandemic changes over time. But they clearly function as a double-edged sword, spreading information rapidly prior to traditional peer review. JAMA Network Open Editors Eli Perencevich, MD, MS and Roy Perlis, MD, MSc join us to discuss on JNOLive.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Don Berwick, MD, MPP, of the Institute for Healthcare Improvement, discusses choices societies and the medical profession can make to improve health care and reduce inequities as we move out of the acute phase of the coronavirus pandemic.

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.

Interview with Hsien-Ho Lin, MD, ScD, author of Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

The US spends more on health care as a proportion of its GDP than any other nation. Will the COVID-19 pandemic reduce or accelerate that spending? Sherry Glied, PhD, Dean and Professor of Public Service at New York University, explains. Recorded Monday, April 27, 2020.

Read the article

The Potential Effects of Coronavirus on National Health Expenditures

Steven M. Bradley, MD, MPH joins JAMA Network editors to discuss a randomized clinical trial evaluating the safety and efficacy of 2 chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19). Read the editorial here: https://ja.ma/2JC5sGx.

JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

A new exhibit on the 1918 flu pandemic asks: What is an individual's responsibility to their community during a pandemic? Exhibit curator Jane Boyd and museum manager Nancy Hill take Jennifer Abbasi on a tour of the medical museum's new exhibit just weeks before the COVID-19 outbreak first emerged.

Pandemic Part 1: 1918 Flu Pandemic and COVID-19

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Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Medical historian Howard Markel, MD, PhD, director of the University of Michigan's Center for the History of Medicine, speaks with JAMA Fishbein fellow Angel Desai, MD, about lessons from the devastating 1918 flu pandemic. Markel discusses his research into the effects of social distancing on US death rates during the worldwide outbreak.

Pandemic Part 2: A Trip to Philadelphia’s Mutter Museum

Read the article:

Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung compliance. Ventilatory support for COVID-19 patients requires higher than normal tidal volumes with minimal PEEP and allowance for higher than usual serum CO2 levels. How the unique pathophysiology of respiratory failure should be treated is discussed by John J. Marini, MD, professor of medicine at the University of Minnesota.

Marc Lipsitch, DPhil, an infectious diseases epidemiologist developing biological and modeling approaches to pathogen transmission and outbreaks, discusses evolution of the COVID-19 pandemic in summer and fall 2020. Originally recorded April 22, 2020.

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.

Rochelle Walensky, MD, MPH, of Harvard University discusses public health strategies and policies for lifting shelter-in-place and quarantine and for returning the US to a new post-first-wave normal. Recorded Monday April 20, 2020.

New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.

Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.

NIAID Director and Presidential Coronavirus Task Force Advisor Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner, MD. Recorded April 8, 2020.

US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.

Shortages of face masks and N95 respirators have forced clinicians and hospitals to reuse these normally disposable items. Ron Shaffer, PhD, former CDC PPE Research Branch Chief, discusses effective sterilization techniques and how to test that the equipment stays protective after sterilization.

Infectious epidemics have always driven change and triggered discrimination in human societies. Frank Snowden, DPhil, Professor Emeritus of History and History of Medicine at Yale University and author of Epidemics and Society: From the Black Death to the Present (Yale University Press, 2019), puts the COVID-19 pandemic in historical context.