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- 28 - Target Trial Emulation for Causal Inference From Observational Data With Dr Hernán
Miguel A. Hernán, MD, DrPH, professor of epidemiology, Harvard T.H. Chan School of Public Health, discusses Target Trial Emulation: A Framework for Causal Inference From Observational Data with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content:
Target Trial EmulationThu, 02 May 2024 - 27min - 27 - On Deep Learning for Medical Image Analysis With Dr Carin
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses On Deep Learning for Medical Image Analysis with Lawrence Carin, PhD. Related Content:
On Deep Learning for Medical Image AnalysisThu, 04 Apr 2024 - 22min - 26 - Patient-Reported Outcome Measures in Clinical Research With Drs Weinfurt and Reeve
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Patient-Reported Outcome Measures in Clinical Research with Kevin P. Weinfurt, PhD, and Bryce B. Reeve, PhD. Related Content:
Patient-Reported Outcome Measures in Clinical ResearchThu, 07 Mar 2024 - 22min - 25 - Immortal Time Bias in Observational Studies With Dr Kabir Yadav
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Immortal Time Bias in Observational Studies with Kabir Yadav, MDCM, MS, MSHS. Related Content:
Immortal Time Bias in Observational StudiesThu, 04 Jan 2024 - 15min - 24 - Adjustment for Baseline Characteristics in Randomized Clinical Trials
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjustment for Baseline Characteristics in Randomized Clinical Trial with Lars W. Andersen, MD, MPH, PhD, DMSc. Related Content:
Adjustment for Baseline Characteristics in Randomized Clinical TrialsThu, 07 Dec 2023 - 18min - 23 - Odds Ratios—Current Best Practice and Use With Dr Norton
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Odds Ratios—Current Best Practice and Use with Edward C. Norton, PhD. Related Content:
Odds Ratios—Current Best Practice and Use Types and Distribution of Payments From Industry to Physicians in 2015Thu, 02 Nov 2023 - 12min - 22 - Estimands, Estimators, and Estimates With Dr Little
Roger J. Lewis, MD, PhD, discusses Estimands, Estimators, and Estimates with Roderick J. Little, PhD, in the JAMA Guide to Statistics and Methods series. Related Content:
Estimands, Estimators, and EstimatesThu, 03 Aug 2023 - 22min - 21 - Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses With Dr Smith
Roger J. Lewis, MD, PhD, discusses Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses with Valerie A. Smith, DrPH. Related Content:
Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses of Clinical TrialsThu, 04 May 2023 - 18min - 20 - Time-to-Event Analysis With Dr Tolles
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Time-to-Event Analysis with Juliana Tolles, MD, MHS. Related Content:
Time-to-Event AnalysisFri, 03 Mar 2023 - 11min - 19 - Adjusting for Nonadherence or Stopping Treatments With Drs Adler and Latimer
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjusting for Nonadherence or Stopping Treatments with Amanda I. Adler, MD, PhD, and Nicholas Latimer, PhD. Related Content:
Adjusting for Nonadherence or Stopping Treatments in Randomized Clinical TrialsThu, 05 Jan 2023 - 17min - 18 - Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data With Dr Lachin
JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data with John M. Lachin, ScD. Related Content:
Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing DataThu, 03 Nov 2022 - 17min - 17 - Using Latent Class Analysis to Identify Hidden Clinical Phenotypes With Dr Heather G. AlloreThu, 01 Sep 2022 - 17min
- 16 - Use of Run-in Periods in Randomized Trials With Dr Armitage
JAMA Statistical Editor Roger Lewis, MD, PhD, discusses Use of Run-in Periods in Randomized Trials with Jane M. Armitage, MBBS.
Related Content:
Use of Run-in Periods in Randomized Trials With Dr Armitage Short- and Long-term Effects of a Mobile Phone App in Conjunction With Brief In-Person Counseling on Physical Activity Among Physically Inactive Women: The mPED Randomized Clinical TrialThu, 05 May 2022 - 19min - 15 - Regression Discontinuity Study Design to Estimate Observational Differences With Dr Maciejewski
JAMA Statistical Editor Roger Lewis, MD, discusses Regression Discontinuity Design with Matthew L. Maciejewski, PhD.
Related Content:
Regression Discontinuity Design Using Instrumental Variables to Address Bias From Unobserved ConfoundersThu, 07 Apr 2022 - 17min - 14 - Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony
JAMA Statistical Editor Roger Lewis, MD, discusses Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony.
Thu, 02 Dec 2021 - 23min - 13 - Equipoise in Research—Integrating Ethics and Science in Human Research
Roger J. Lewis, MD, PhD, discusses Equipoise in Research—Integrating Ethics and Science in Human Research with Alex John London, PhD
Related Content:
Equipoise in Research—Integrating Ethics and Science in Human Research
Thu, 07 Oct 2021 - 21min - 12 - Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials
Roger J. Lewis, MD, PhD, discusses Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials with Melanie Quintana, PhD
Related Content:
Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial Incorporating Adult Evidence Into Pediatric Research and Practice: Bayesian Designs to Expedite Obtaining Child-Specific EvidenceThu, 02 Sep 2021 - 27min - 11 - Cost-effectiveness Analysis for Clinicians
Cost-effectiveness analysis defines trade-offs between costs, harms, and benefits of alternative treatments and combines them into a single metric, the incremental cost-effectiveness ratio (ICER), that can inform decisions about which interventions to recommend when limited resources are available. Gillian Sanders-Schmidler, PhD, professor of population health sciences and medicine at Duke University, explains the method in terms clinicians can understand.
Related Article:
Cost-effectiveness Analysis for CliniciansThu, 05 Aug 2021 - 18min - 10 - Multiple Comparison Procedures from the JAMA Guide to Statistics and Methods
JAMA Deputy Editor Edward Livingston, MD, discusses "Multiple Comparison Procedures" with Dr. Jing Cao, PhD
Thu, 04 Mar 2021 - 22min - 9 - Logistic Regression—What It Is and How to Use It in Clinical Research
Logistic regression is one of the most commonly used statistical analytic tools in the medical literature. William Meurer, MD, from the University of Michigan, and Juliana Tolles, MD, from UCLA, discuss a JAMA Guide to Statistics and Methods article they wrote entitled “Logistic Regression Diagnostics: Understanding How Well a Model Predicts Outcomes.”
Related Article:
Thu, 07 Jan 2021 - 32min - 8 - Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods
Roger J. Lewis, MD, PhD, discusses Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods
Related Article(s):
Randomization in Clinical Trials
Thu, 03 Dec 2020 - 23min - 7 - The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment
Cluster randomized trials are performed when an intervention must be delivered to a group of patients like when testing new nursing protocols on award or different means for cleaning beds on a ward. One type of cluster trials is called a stepped-wedge where every cluster in the study ultimately undergoes the intervention. How this works it is explained by Susan Ellenberg, PhD, from the Department of Biostatistics, Epidemiology, and Informatics at the University of Pennsylvania School of Medicine.
Related Article:
The Stepped-Wedge Clinical Trial
Thu, 03 Sep 2020 - 18min - 6 - Minimal Clinically Important Difference: Defining What Really Matters to PatientsThu, 06 Aug 2020 - 11min
- 5 - Sample Size Calculation for a Hypothesis Test With Dr Lynne StokesThu, 02 Jul 2020 - 12min
- 4 - Pragmatic Trials: Practical Answers to “Real-world” Questions With Harold C. Sox, MD
JAMA Deputy Editor Edward Livingston, MD, discusses Pragmatic Trials: Practical Answers to “Real-world” Questions with Harold C. Sox, MD, of PCORI
Thu, 25 Jun 2020 - 21min - 3 - Cluster Randomized Trials: Evaluating Treatments Applied to Groups With William J. Meurer, MD
JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" with William J. Meurer, MD, MS
Thu, 07 May 2020 - 23min - 2 - Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy KajiThu, 06 Feb 2020 - 10min
- 1 - JAMA Guide to Statistics and Methods
Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format.
Purchase the JAMA Guide to Statistics and Methods at:
McGraw-Hill: ja.ma/StatsGuideMH
Barnes and Noble: ja.ma/StatsGuideBN
Amazon: ja.ma/StatsGuideAmazon
Thu, 05 Dec 2019 - 13min
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