The Human Upgrade with Dave Asprey

Peter Diamandis explores how AI is revolutionizing health and longevity, providing insights into cutting-edge technologies and practices that enhance wellness.

Discover how quantum energy and biohacking technologies are intertwined in this detailed exploration with Philipp von Holtzendorff-Fehling.

Ways you can get your mitochondria moving, dial in your nutrition and upgrade your brain, gut and hormones.

In this episode, Jerry Colonna explores how radical self-inquiry and mindfulness profoundly enhance leadership effectiveness and personal growth.

Dr. Anurag Singh discusses the impact of GLP-1 agonists like Ozempic on weight loss and muscle health, emphasizing the importance of mitochondrial health for maximizing benefits and safety.

Discover a fresh take on cancer theories with Mark Lintern, a citizen scientist whose unique perspective offers new hope in understanding and potentially treating cancer.

Florence Williams tackles the seldom-discussed topic of heartbreak and its profound influence on our physical health and psychological growth.

Dr. Aditi Nerurkar explores the complexities of the stress response, offering tools and insights to master resilience and well-being.

The current men’s health pandemic has everything to do with hormones and endocrine disruptors. Learn what to balance and clean up.

You'll learn about the intricacies of how memory works with Dr. Charan Ranganath, a renowned neuroscientist. This episode offers an in-depth look at the role of memory in shaping our perceptions, decisions, and futures.

Discover the power of GLP-1 for natural weight management with Colleen Cutcliffe, PhD. This episode dives into how probiotics can support your body’s own GLP-1 production, leading to reduced cravings, a stronger gut lining, and potential longevity benefits.

Ramon Hervey II, a mastermind manager of stars like Vanessa Williams and Richard Pryor, reveals in "The Fame Game" the realities of fame, emphasizing hard work and excellence over fleeting celebrity.

Bring your hormones into harmony by using food as medicine, keeping the gut healthy, managing stress, avoiding toxins, and finding the right bioidentical replacements.

Dr. Josh Ofman, president of GRAIL, discusses pioneering early cancer detection technologies that are transforming cancer care and the importance of yearly screenings.

The conversation with Dr. Christina Rahm covers her shift to holistic health and covered topics like spirituality, neural feedback, the ethics of health tech, and the environmental influences on well-being.

Maria Menounos reveals the intricacies of her health journey, highlighting the significant role of biohacking in managing and overcoming her medical conditions.

Today, Calley Means joins the show to march onward on his war path to changing the incentives of modern health. He’s a champion of food and lifestyle practices as medicine—and, in May of this year, he’s putting out a new book on the subject which we outline today, called Good Energy. His sister, Dr. Casey Means, is the co-author of Good Energy. You know her from a past appearance on this show and as the founder of Levels so this mission really is a family affair in the best way possible. Going from a food lobbyist to the other side of the fence, Calley is a deeply serious and dedicated champion for the people. But he brings much more to the table today than a polished delivery and a new book; he is also the co-founder of True Medicine, which works to connect tax-advantaged spending to healthy food and exercise.  It’s helped hundreds of thousands of people access affordable care by leveraging the convoluted systems currently in place to block them from doing so—no easy task. In this conversation, Calley lays the foundation for our food culture as it stands today—bleak, corrupt, poisoned, sick, and getting sicker. We deconstruct the layers of federal agencies and historical precedent that have brought us to this point, and we’re direct in our suggestions (demands) on how to fix it. And all the facts are laid bare. Dots are connected in broad daylight, on network television, and within the algorithms that power our social feeds. Our kids are at stake, and the only option is to take affirmative action on what we know is right.  (00:01:19) Calley’s Inspirations & Metabolic Mission (00:11:16) Redefining the Meaning of Medicine  (00:19:21) Is America a Viable Place To Raise Healthy Kids? (00:30:41) Meaningfully Changing Healthcare Incentives (00:42:56) Now What—How Does Society Make Positive Change? (00:49:34) The Media’s Role in Society’s False Narratives (00:56:49) Undoing the Damage of the Food Pyramid Sponsors ARRC LED | The perfect device for daily home use. For more information visit arrcled.com. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Good Energy: The Surprising Connection Between Metabolism and Limitless Health Truemed: truemed.com The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How can we make our furry best friends live longer, healthier lives? A true pioneer in this field, Dr. Matt Kaeberlein, is here to unpack this important subject while highlighting the crossover between human and canine longevity. You read that right; this episode isn't just for dog lovers—it's a deep dive into longevity for humans, too.  Dr. Matt Kaeberlein, who's the CEO of Optispan and a key figure in the Dog Aging Project, brings a wealth of knowledge from his distinguished career in aging and healthspan research. He's an Affiliate Professor at the University of Washington and a notable figure in gerontology, recognized by organizations like the American Association for the Advancement of Science and the Gerontological Society of America.  Matt's work is groundbreaking, demonstrated in over 250 scientific papers on aging, numerous prestigious awards, and he's even a Fellow of several aging associations. He's on a mission to unlock the secrets of aging, not just in humans, but in our four-legged companions as well. We explore the accuracy of measuring age with telomeres versus epigenetics and get into the nitty-gritty of diet's impact on longevity for both dogs and humans, reminding us it's not just about living longer, but living well. Matt explains the impressive trial results on rapamycin for reducing age-related inflammation, a breakthrough that's not just exciting for us but also for our pets. Finally, we touch on how AI is revolutionizing our approach to understanding and extending our healthspan. For those who want to get more involved, check out dogagingproject.org. It's not every day you meet someone who's made such significant strides in understanding aging across species. So whether you're a pet parent or just passionate about extending your own health span, this episode is for you. (00:01:31) Dogs Are the Bridge Between Lab Studies & Human Longevity (00:11:09) Exploring the Impact of Diet on Longevity (00:18:50) How Our Unique Biology Impacts Aging (00:26:33) Exploring How Size & Diet Impact Health Across Species (00:37:55) Fighting Age-Related Inflammation with Rapamycin (00:56:40) AI Interventions for Longevity Testing Sponsors ARMRA | Try it out for yourself at TryARMRA.com. Use code “Dave” to get 15% off your first order STEMREGEN | Go to STEMREGEN.co/Dave for 20% off. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Learn More: dogagingproject.org Website: optispan.life X: @mkaeberlein Listen: The Optispan Podcast with Matt Kaeberlein The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’m excited to welcome back Jewels Arnes, an author, ascension coach, and the founder of BioQuantum Skincare Technology. Jewels has more than 30 years of experience in energy medicine and intensive consciousness work.  In today’s episode, Jewels explains scalar waves, ORMUS, and the quantum level. She shares how these concepts all contribute to her BioQuantum Skincare line and the intention she poured into the products. We also talk about how and why Jewels moved away from psychedelics and regular meditation, and how she tunes into frequencies without them.  Plus, we get into the spiritual ego, how to master your triggers, the frequency of DMT, and Jewels’ role as an ascension coach. Unlike my analytical brain, Jewels sees the world through frequencies, so this was a fun conversation with fresh perspectives.  (00:01:13) Dave’s Experience with ORMUS (00:06:59) Dangers of the Spiritual Ego (00:15:02) The Sphere of Spirituality & Science (00:18:11) How To Tune Into Frequencies (00:23:34) Cultivating Awareness of Our Triggers (00:27:57) Creating Products with Intention (00:32:22) What Is ORMUS? (00:38:43) Operating at the Quantum Level (00:49:22) The Frequency of DMT (00:55:23) Unboxing the BioQuantum Product Line (00:56:39) What Is Ascension Coaching? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Shop: becomingbioquantum.com/dave to save 22% on the Scalar 33 ORMUS Activator  Website: becomingbioquantum.com Instagram: @jewels.arnes Instagram: @becomingbioquantum  Podcast: becomingbioquantum.com/podcast YouTube: @BecomingBioQuantum  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What is the role of Ego? Is AI going to kill us? Is there hope for the future of our species? These are just a few of the big questions you’ll tackle in today’s enlightening and esoteric episode. I’m joined by Teal Swan, a thought leader, bestselling author, and international speaker who is on a mission to reduce human suffering. After a challenging upbringing, Teal emerged with a unique ability to talk about psychology, shadow work, and the nature of our world.  Teal shares the unusual and special way she sees the world. We talk about her ESP powers, how to identify a narcissist, and her favorite dimensions. We also get into the divine masculine vs. the divine feminine, the nature of ego, and how to build trust in the world and others.  (00:01:37) Finding Forgiveness in Betrayal (00:11:34) Teal’s Take on Artificial Intelligence (00:14:43) Teal Swan’s ESP Powers (00:23:22) Exploring Intention in Art (00:25:47) Upgrading Human Software & Hardware (00:27:48) How Teal Functions in the “Real” World (00:32:39) Trusting in the World (00:35:19) What’s the Nature of Ego? (00:39:14) Discovering Different Dimensions (00:42:46) Divine Feminine vs. Divine Masculine (00:52:31) Is There Hope for the Future of Our Species? (00:53:58) What Is a Synchronization Workshop? Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-Day Free Mitosynergy | Get 15% off now at Mitosynergy.com/Dave Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: tealswan.com Instagram: @tealswanofficial YouTube: @TealSwanOfficial TikTok: @tealswanlive Podcast: Teal Swan The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is none other than Shawn Stevenson. If you’re not already familiar with Shawn’s work, he’s the author of the USA Today National bestseller Eat Smarter, the international bestselling book Sleep Smarter, and the creator of the widely popular health podcast, The Model Health Show. Shawn is one of those guys who embodies peace and calm, after an impressively transformative journey stemming from a background of health challenges at least as severe as mine. After recovering, he became a researcher and nutritionist experienced in biology and nutritional science.  We dive into a crucial element of biohacking I am always keen to highlight—friendship, or in this case, community. Based on research from Shawn’s latest book, Eat Smarter Family Cookbook, we talk about his current mission on the path to wellness: creating a culture of wellness around the dinner table, how communal meals impact our health and longevity, and filling the void of connection we all so desperately need these days.  Shawn shares insights from his own family’s dinner table, his tips for implementing family meals into your weekly routine, and the encouraging science and data behind how it supports physical and spiritual nourishment, nervous system regulation, stress management, and more. If you like this episode, I encourage you to go pick out a good cut of meat and cook food for someone you care about—or simply do anything that's an act of service that nourishes another human being. Here’s to cultivating strong relationships, imbuing our food with love, and honoring the act of nourishing ourselves and our families. (00:01:16) Cultivating Peace & Presence Through Nervous System Regulation (00:10:00) Cultural Connections to Health, Longevity & Childhood Obesity (00:25:20) Family Dinners for Nourishment, Mindfulness & Building Stronger Bonds (00:43:45) Kids in the Kitchen: Fostering Enjoyment, Skill & Service in Cooking (00:59:48) Heart Meditations, Trauma Healing & the Science of Emotional Exchange Sponsors Bioptimizers | Go to Bioptimizers.com/Dave for 10% off any order. LeelaQ | Visit LeelaQ.com/Dave for 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Podcast: The Model Health Show Instagram: @shawnmodel YouTube: The Shawn Model Read: Eat Smarter Family Cookbook by Shawn Stevenson The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest has the coolest title I’ve ever heard—mind architect.  Peter Crone is a world-renowned spiritual teacher, mind-body wellness coach, and life transformation expert. He’s worked with everyone from athletes, to actors, to billionaire CEOs, to everyday people trying to do their best. Peter helps people achieve spiritual freedom, mental peace, and physical vitality, which all align with biohacking in a big way. In this episode, we dig deep into the limiting beliefs that shape our behavior and relationships. We talk about discerning between reality and the stories we tell ourselves. Peter gives advice on overcoming perfectionism, strengthening your intuition, and recognizing your innate value. We also explore how to reframe language, the value of curiosity, and how to harness losses into learnings that unlock your greatest potential. It’s a fascinating conversation.  You can hear more from Peter at the upcoming Biohacking Conference. Get your tickets at biohackingconference.com.  (00:03:33) Where Biohacking Meets Energy Work (00:06:28) Accessing a Spiritual State Without Drugs (00:11:04) Recovering From Perfectionism (00:19:14) Reality vs. the Stories We Tell Ourselves (00:29:42) Healing Wounds From Birth (00:38:31) Why Fear Is the Enemy of Health (00:43:18) How To Train & Strengthen Intuition (00:56:01) Recognizing Your Innate Value (01:03:30) How Can We Learn From Our Elders? (01:06:19) Peter’s Freedom Program Sponsors Timeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: petercrone.com Instagram: @petercrone Facebook: Peter Crone - The Mind Architect  TikTok: @petercroneofficial  YouTube: @PeterCroneOfficial The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we're diving into a topic that's on everyone's mind, but often misunderstood: gluten. Joining the show on this gluten-decoding mission is none other than Dr. Peter Osborne, aka the Gluten-Free Warrior. Dr. Osborne is a powerhouse of knowledge in nutritional health, particularly regarding gluten sensitivity and food allergies.  As the founder of Gluten Free Society, the author of the bestseller, No Grain No Pain, and the host of the Glutenology MasterClass Series, he's at the forefront of functional medicine, helping countless individuals combat chronic and autoimmune diseases.  His insights are crucial for anyone navigating the complexities of a gluten-free life. In this episode, we explain why gluten isn’t good for anyone—even if you don’t have symptoms or a diagnosed celiac problem. As a foundation, we lay out the differences between gluten sensitivity and celiac disease, covering the surprising connections between dairy, gluten allergies, and mold.  Dr. Osborne also highlights why common gluten-free substitutes like corn, oats, and rice aren't the safe havens we wish we were. You’ll hear about the nefarious ways Big Food is keeping our country sick and how to start taking charge of your own health in simple, free ways. Dr. Osborne shares his recommended diet, the rule of thirds, and how to effectively shift your eating habits. He recognizes the frustration and struggle many people face in finding effective professional help, and shares his tips for spearheading your own healing while collaborating with competent professionals. This episode isn't just about gluten; it's a deep dive into understanding your body, your diet, and how to collaborate with your doctor to find the health solutions that work for you. (00:01:48) Why We Should All Be Gluten Free (00:11:46) Big Food’s Role in Our Declining Health (00:28:31) When to Enjoy (and Avoid) Sugar, Soybeans & High Oxalate Foods (00:42:39) Change Your Diet & Biohack Your Way to Better Health (01:00:15) How To Respectfully Advocate for Your Own Health Sponsors BEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order. Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: drpeterosborne.com Read: No Grain, No Pain by Peter Osborne YouTube: Peter Osborne Instagram: @drosborne The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we’re talking about something a little different—the “weird,” esoteric, metaphysical stuff. I’m joined by Laura Coe, who was a successful healthcare tech entrepreneur before selling her company and returning to her passion for philosophy. She is now an author, certified life coach, and Akashic Records reader.  Never heard of the Akashic Records? Laura explains exactly what they are, and how they can help you understand yourself on a deeper level to find more joy, peace, and prosperity in your life. We explore the big questions… Who can access the Records? How do you know if they’re even real?  Then, we get into the nitty gritty… How do you learn to read them? What can you ask and not ask? Can they help you sell your house or make more money?  Laura and I also talk about how to tap into your intuition as an entrepreneur, the stigmas against spirituality, and why more of us than we think probably have psychic gifts. If you’re skeptical of this stuff, I’m going to ask you to suspend your disbelief and listen with an open mind. Laura’s perspective will give you a lot to think about. Why not give it a try?  (00:03:47) What Are The Akashic Records? (00:13:15) The Akashic Records as a Grid of Interconnection (00:18:47) Validating The Akashic Records for Skeptics (00:23:37) Coming Out As Spiritual (00:26:53) How Long Does It Take To Learn The Akashic Records? (00:29:42) The Craziest Questions People Ask (00:32:39) Listening to Your Inner Knowing (00:38:01) What Can’t You Ask The Akashic Records? (00:41:55) Sentences That Open the Records (00:47:22) Healing Yourself Through Healing Others (00:48:54) Can It Help You Sell Your House? (00:56:11) Taking the “Woo Woo” out of The Akashic Records Sponsors Mitosynergy | Get 15% off now at Mitosynergy.com/Dave Calroy.com | Head over to Calroy.com/Dave for an exclusive discount Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: lauracoe.com The Little Soul School: littlesoul.school Read The Nature Of Series: lauracoe.com/books Instagram: @laurascoe The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today I’m talking with one of the most sought-after celebrity trainers on the planet. Jason Walsh has trained stars like Matt Damon, Miles Teller, Brie Larson, and Bradley Cooper for some of the most physically demanding roles of their careers.  He’s also the founder of Rise Nation, a global fitness studio powered by the VersaClimber, where you train like an athlete.  On today’s episode, we talk about how Jason rose to success as a celebrity trainer. He shares the moments that defined his life and career, plus his advice for anyone who wants to get started in the fitness industry. We also go deep on the painful parts of entrepreneurship—unpacking the betrayals and heartbreaks we’ve both experienced as founders.  We explore ways to train your brain and your body for resiliency, and how to redefine forgiveness as an energetic shift. We also talk about Jason’s new protein company, Rise 311. Plus, his take on why you don’t need to train for an hour a day to get results.  (00:02:06) How Jason Became a Celebrity Trainer  (00:22:22) The Rewards of Being Disciplined  (00:25:40) How to Rise in Your Fitness Career (00:33:52) Building Rise Nation Step by Step  (00:40:13) The War Against Small Businesses  (00:42:47) Heartbreaks & Betrayals in Business  (00:48:23) Train Your Brain to Reframe Trauma  (00:53:47) Redefining Forgiveness  (01:00:33) The Rise of Rise 311 (01:02:32) Finding Joy & Resilience  Sponsors Mitosynergy | Get 15% off now at https://Mitosynergy.com/Dave Calroy | Go to https://Calroy.com/Dave for an exclusive discount Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: rise-nation.com Rise 311: rise311.com Instagram: @risenation Jason’s Instagram: @risemovement TikTok: @climbrisenation The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Blood sugar management as a biohack captures attention for its innovative approach to health. Today's guest, Jessie Inchauspé, stands out as an expert in guiding practical glucose management, smarter nutritional choices, and unveiling the intricate relationship between diet, blood sugar levels, and overall well-being. Behind the popular Instagram account @GlucoseGoddess, Jessie educates millions on groundbreaking food habits and has achieved notable success as a French biochemist and New York Times bestselling author, with over a million copies sold of her works, "Glucose Revolution" and "The Glucose Goddess Method," in 40 languages. Her unique combination of mathematics and biochemistry expertise opens up the secrets of blood sugar and its significant impact on physical and mental health. The conversation zeroes in on Jessie's mission to make complex science accessible through simple, transformative tips.  Topics include her groundbreaking research, The Glucose Method study, the launch of her Anti-Spike supplement, and her signature four hacks for glucose management after consuming carbs. The dialogue also covers the benefits of real versus fake sugar, the underlying causes of insulin resistance and diabetes, and how blood sugar spikes influence aging. This episode unveils Jessie's remarkable discoveries and biohacks for glucose management, which are crucial for fertility, PCOS, and understanding the health impacts of lifestyle choices like alcohol and nicotine. Jessie's practical insights offer a path to enjoying favored foods with minimal bodily impact, appealing to both biohacking aficionados and those embarking on a health journey. (00:02:28) Understanding Glucose’s Role in Our Health (00:14:27) Enjoying Carbs Without Negative Side Effects (00:23:27) The Real Cause of Insulin Resistance & Diabetes (00:34:23) Addressing Alcohol, Nicotine & The French Paradox (00:54:22) The Glucose Goddess Method Study (01:05:47) Glucose Management for Fertility, PCOS & PMS Cravings Sponsors Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order. Sunlighten | Head to Sunlighten.com/dave to save up to $600 when you order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: glucosegoddess.com Instagram: @glucosegoddess  Read: Glucose Revolution by Jessie Inchauspé Read: The Glucose Goddess Method by Jessie Inchauspé The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today we're talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training—both methods to gain, and keep, muscle mass in your body without living in the gym. I’m joined by strength expert, entrepreneur, past guest of the show, and PhD, John Jaquish. John has spent years researching and developing improved approaches to health. Inventor of X3, a technology that is proven to develop muscle much faster than conventional weight lifting with the lowest risk of joint injury, Dr. Jaquish’s methods are used in training the world's most elite athletes as well as Olympians. Aligning with the most basic tenet of biohacking, if you can achieve all of your physical or athletic goals in half the time of your competitors, why not explore the option? John is as gracious as he is informed in this one, detailing the benefits of variable resistance training and indulging me in a super deep dive into diet and nutrition experimentation, testosterone replacement therapy, and efficient muscle growth. You’ll learn what he eats every day to look as good as he does. You’ll get repetition-count-specific recommendations on ultra-quick workout routines. And you’ll learn the very surprising amount of carbohydrates I ingest every single day (a number that will shock many of you). Sponsors BEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order. ARMRA | Try it out for yourself at tryarmra.com. Use code DAVE to get 15% off your first order. (00:02:39) Masterclass on Efficient Muscle Building (00:16:43) How are Shaolin Monks & Gymnasts So Strong?   (00:23:46) Testosterone Replacement Therapy (TRT) (00:38:40) How Protein Impacts Muscle Growth (00:47:55) Breakthrough Personal Research on Carbohydrates (00:58:31) Weight Lifting is a Waste of Time Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: jaquishbiomedical.com Instagram: @drjaquish YouTube: Jaquish Biomedical Read: Weight Lifting Is a Waste of Time Read: Osteogenic Loading: A New Modality To Facilitate Bone Density Development How to Build Strength Faster – John Jaquish, Ph.D. #863 Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D. #862 The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Welcome to a special Upgrade Spotlight Edition, where I introduce you to someone who's genuinely changing the game. Our carefully selected guest today is a renowned pharmacist, an author, and a pioneer in biohacking for skin longevity: Dr. Nayan Patel.  Dr. Patel is a trailblazer in the world of antioxidants, specifically glutathione. If you've been following biohacking or are a regular listener, you know that glutathione is a key antioxidant with vital functions, including skin health. Dr. Patel's expertise in absorbable glutathione and anti-aging sciences is unparalleled. Dr. Patel holds a unique patent for transdermal glutathione delivery, a groundbreaking method of introducing this crucial antioxidant directly through your skin with his company Auro Wellness. His book, The Glutathione Revolution, dives deep into this topic.  In this episode, we delve into why glutathione is essential for skin longevity. Dr. Patel shares insights on his innovative formula and technology for absorption at Auro Wellness, which has shown promising results in reducing fine lines, cellulite, and even promoting hair growth.  As someone who champions scientifically-backed products and real results, I'm excited to discuss how Dr. Patel's work is a true game changer. I know the power of glutathione. I've been using it for nearly two decades, especially during my battle with toxic mold exposure.  And now, thanks to innovators like Dr. Patel, we're moving from intravenous methods to transdermal applications—it's truly revolutionary. For those eager to try, visit aurowellness.com and use code DAVE10 for a discount. (00:01:14) Biohacking Benefits of Glutathione & New Absorption Technology (00:08:32) The Auro Skincare Stack & How Glutathione Enhances Skin Longevity (00:20:13) Reducing Cellulite & Fine Lines with Glutathione  (00:35:01) Glutathione for Hair Growth & Toxin Removal Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Shop Auro Wellness: aurowellness.com (use code DAVE10 for 10% off) Read: The Glutathione Revolution by Dr. Nayan Patel and Dr. Mark Hyman The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’m pumped to welcome one of the hosts of the Mind Pump Podcast, top trainer and entrepreneur Sal Di Stefano. Mind Pump pulls back the curtain on the health, fitness, and nutrition industries, cuts through the pseudo-science, and offers science-backed solutions for enhancing performance while emphasizing health.  Sal started his journey in the gym at age 14, and I admire how he’s steadily grown a meaningful business around biohacking fitness.  On today’s episode, we take on some weighty topics like weight training vs. cardio, why veganism is dangerous, and why reverse dieting may actually be the key for results. Sal explains his fitness philosophy, which focuses on functional movement, reframing your mindset around exercise, and consistency above all else.  We also get into the nutrition side of things. Sal and I break down how much protein you should be eating per day, plus our favorite proteins—and the evil ones we avoid. We also talk carbs. Do they make you fat? How do they impact performance? What are the best sources? Then, we get fired up talking about how you can fire up your metabolism.  This episode is for everyone, from gym newbies to serious bodybuilders. And check out my episode on The Mind Pump Podcast to get a double dose of me and Sal (watch or listen). (00:01:03) Are Bodybuilders the Edgiest Biohackers? (00:04:51) Strength Training vs. Cardio (00:12:27) Strength Training as a Longevity Tool (00:16:32) Moving Toward Functional Movement (00:21:10) Reframing Movement in Your Mind (00:29:17) Why Veganism Is Dangerous (00:33:27) Do Carbs Make You Fat? (00:38:34) Should You Reverse Diet? (00:40:54) How Much Protein Should You Eat? (00:50:18) Is There Any Good Reason To Eat Chicken? (00:55:10) Winning Carb Choices (00:59:42) Sal’s #1 Recommended Supplement (01:02:00) The Single Biggest Fitness Mistake Sponsors Mitosynergy | Get 15% off now at Mitosynergy.com/Dave 40 Years of Zen | Upgrade Your Brain in 5 Days by going to 40YearsOfZen.com/Dave Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Mind Pump Podcast: mindpumppodcast.com Mind Pump Training Protocols: mindpumpmedia.com/maps-fitness-products Mind Pump Instagram: @mindpumpmedia Sal’s Instagram: @mindpumpdistefano X: @mindpumpsal TikTok: @mindpumpmedia YouTube: @MindPumpShow The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dive into yoga nidra with Tracee Stanley, a renowned teacher and author who unveils the transformative power of rest. Her book, "Radiant Rest," showcases the vital role of recovery in biohacking, advocating for the strength found in stillness.  Tracee, with over twenty years of experience and collaborations with icons like Marianne Williamson, is a leader in the realm of deep rest and clarity. Her latest work, "The Luminous Self," deepens this exploration, aligning with our aim to unlock inner power for a fulfilling life.  Today, we delve into yoga nidra's science, its profound effects on our brain, and how it connects us to our roots, reshapes habits, and promotes deep healing. Tracee's approach not only offers a pathway to better understanding and caring for ourselves but also redefines our relationship with rest and the world. Her insights are essential for anyone seeking a holistic biohack for body and mind wellness, providing clarity, compassion, and the gift of deep rest. (00:00:40) Accessing Real Rest & Peace With Yoga Nidra (00:12:25) One Free Daily Practice for Better Sleep, Focus & Productivity (00:26:34) Exploring Death Practices & Connecting to Nature (00:42:34) Creating a Legacy of Peace: Passing on Indigenous Traditions & Teachings (00:53:50) Healing a Sleep Deprived World & Confronting the Root Cause of Suffering (01:08:13) Exploring Tracee’s Tools for Connection & Healing Sponsors Calroy | Calroy.com/Dave for an exclusive discount Bioptimizers Blood Sugar Breakthrough | Go to BloodSugarBreakthrough.health/Dave and use code “Dave10” for 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Read: The Luminous Self by Tracee Stanley Read: Radiant Rest by Tracee Stanley Website: traceestanley.com Instagram: @tracee_stanley The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s show is a masterclass in improving your skin without going under the knife. I’m excited to welcome back Dr. Rob Whitfield, an Austin-based plastic surgeon who specializes in breast implant removal surgeries and advanced cosmetic procedures. He invented the famous “No-Cut” Facelift, which revolutionized non-surgical facelifts for a more natural appearance.  I worked with Rob on a “No-Cut” Facelift, and he removed excess skin from my back after my weight loss. I got to be the guinea pig, and now I’m sharing everything I learned with you. On today's episode, I recount my experience and results with these procedures. Dr. Rob explains what a “No-Cut” Facelift is, plus other non-surgical procedures to tighten fat, remove excess skin, and reduce wrinkles.  We talk about radio frequency-assisted lipolysis, SoftWave therapy, Morpheus8, and a whole lot more. Plus, we get into foods that hurt your skin, injectable vs. topical peptides, and biohacking skincare. Basically, it’s everything you need to know for younger, healthier-looking skin. And let’s face it, we all want that.  (00:01:58) Dave’s Experience Working With Dr. Rob (00:08:48) What Is a “No-Cut” Facelift? (00:19:10) Shrinking Fat With Radio Frequency Assisted Lipolysis (00:22:13) Zoom Lifts & More Non-Surgical Procedures (00:29:02) What Is SoftWave Therapy? (00:33:28) Biohacking for Skincare (00:34:47) Morpheus8: Good or Bad? (00:35:53) Treatments for Excess Skin (00:37:44) How Bad Are BBLs? (00:41:57) Does Your Skin Have a Biological Clock? (00:45:32) Foods That Hurt Your Skin (00:48:18) Topical vs. Injectable Peptides (00:50:17) The Bright Side of Sun Exposure (00:53:42) What To Do for Your Skin at 25 Sponsors Leela Q | Visit LeelaQ.com/Dave for 10% off. Timeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: drrobertwhitfield.com The HARP™️ Method: harp.health Instagram: @breastimplantillnessexpert Instagram: @drrobwhitfield Facebook: Dr. Rob Whitfield MD YouTube: @breastimplantillnessexpert TikTok: @drrobertwhitfield How Breast Implants Compromise Your Health and Make You Sick #1043 The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Inflammation is at the root of everything. More inflammation means less energy and a higher risk of every disease. Today, we’re digging into exactly why inflammation is so insidious with functional medicine nurse practitioner Maggie Berghoff.  Maggie is a USA Today National Best-Selling author of the book Eat to Treat: Your Three-Step Plan To Reduce Inflammation, Detoxify Your Life, And Heal Your Body. She is also the founder of wellness supplement and non-toxic home line DETOXDaily.  In this episode, we talk all about inflammation—what causes it, how it hurts us, and how to combat it. We explore all the different types of inflammation, including physiological vs. psychological inflammation– and dig into how inflammation intersects with hormone health, thyroid function, and metabolic syndrome.  Maggie also shares her perspective about shedding shame around eating, and why perfectionism can be even more toxic than actually toxic foods. Plus, I share a lot of horrifying (but medically useful) information about urine. You’ll be equally intrigued and grossed out.  (00:01:29) The Ills of Inflammation (00:07:23) Physiological vs. Psychological Inflammation (00:15:00) 3 Things That Cause Inflammation (00:25:26) Are We More Inflamed Now Than Ever? (00:27:19) Where Do You Start Combating Inflammation? (00:30:09) What Is Your Inflammation Type? (00:35:50) When Your Hormones Are in Havoc (00:46:58) Metabolic Syndrome’s Role in Inflammation (00:49:22) The Nightmare of Poor Sleep (00:55:18) Shedding Shame Around Food (01:02:20) Why Not Just Take Aspirin? Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/dave for a 15 day free trial Stemregen | Go to Stemregen.co/dave for 20% off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: maggieberghoff.com Eat To Treat: eattotreat.com DETOX Daily: yourdetoxdaily.com Instagram: @maggie_berghoff Facebook: Maggie Berghoff  TikTok: @maggie_berghoff  Linkedin: Maggie Berghoff  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Meet a man who makes miracles happen. Today, I’m joined in the studio by Hal Elrod, author of the international bestseller The Miracle Morning and his newest book, The Miracle Equation. After overcoming multiple near-death experiences and financial hardships, Hal channeled his adversity into helping others overcome their own challenges. His Miracle Morning approach has impacted millions of lives. On today’s episode, Hal tells us all about his updated version of The Miracle Morning. He explains SAVERS, the six foundational practices that will transform your morning and change your life. We also talk about tips for hacking your sleep, productivity, and relationships.  Hal shares the stories of his devastating car accident and rare cancer diagnosis—and the superpowers he gained from coming back to life. We explore how these near-death experiences changed his perspective on life and what he values most. He also tackles some tough questions… Should we try to help everyone? What does it mean to be a “man”? And what does it take to truly serve others? There’s so much to take away from Hal’s refreshing and optimistic perspective.  (00:03:20) Creative Ways To Hold Yourself Accountable (00:13:57) Ditching Veganism (00:21:08) Hal’s Near-Death Experiences (00:27:35) Taking Your Health in Your Hands (00:29:37) Did Hal Come Back With Superpowers? (00:31:55) Are You Supposed To Help Everyone? (00:40:51) How the Miracle Morning Changed Hal’s LIfe (00:43:42) What Does It Mean To Be a “Man”? (00:51:25) Customizing Your Morning To Meet Your Needs (00:54:05) The Six Savers for Success (00:56:53) Tips To Save Your Sleep (01:01:51) The MVP of Personal Development Practices (01:06:14) Nourishing Our Connections Sponsors Viome | Go to Viome.com/Dave and save $110 on the full-body intelligence test.  Neurohacker | Go to Neurohacker.com/Dave and try it risk free for up to 100 days. Use code “DAVE” at checkout for 15% now. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Read: The Miracle Morning and The Miracle Equation Website: halelrod.com Facebook: Hal Elrod X: @HalElrod YouTube: @HalElrod The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Imagine the benefits of stem cell regeneration without needles or a high cost. Today, I'm excited to introduce Christian Drapeau, inventor of a groundbreaking plant-based stem cell product for health and longevity. Christian is more than a scientist; he's a stem cell expert and herbalist, pioneering plant-based stem cell enhancers. Yes, plants and stem cells together! His background from McGill University and work at Stemtech International make him a leading voice in stem cell science.  His book, 'Cracking the Stem Cell Code,' reveals how our bodies use stem cells for repair, and his latest research shows how aquatic plants can boost stem cell production, like nature's own fountain of youth. We'll explore how Christian's journey in ancient herbalism led to innovative discoveries in stem cell enhancement and clarify the difference between traditional procedures and products like STEMREGEN.  Stay tuned for key answers: How do stem cells promote longer, healthier lives? What's the truth about stem cells and cancer? When's the best time to start using these products? I'll also share my personal routine for maximizing stem cell supplement effects. If you're excited about affordable, effective health benefits, try STEMREGEN. Visit stemregen.co/dave to save 20% on your order. (00:01:09) STEMREGEN: Understanding The Herbalism x Stem Cell Crossover (00:12:21) Stem Cells & Longevity 101 (00:23:55) The Historical Context of Healing & Longevity with Plants (00:32:05) Affordability & Cancer Prevention with STEMREGEN (00:44:27) Preventing Kidney Stones & Lowering Your pH  (00:57:37) Dave’s Biohacking Stack for STEMREGEN Enhancement  (01:05:51) Improving Mitochondrial Function & Measuring Age Sponsors Bioptimizers | Go to Bioptimizers.com/dave, and use code "Dave10" for 10% off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: stemregen.co/dave Instagram: @stemregen YouTube: STEMREGEN The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re digging into specifics about food that you haven’t heard on the show before. This one may very well influence you to rethink your “healthy” diet and change how you feel about food completely. To get there, I’m excited to welcome back Teri Cochrane, an integrative practitioner and pioneer in personalized healthcare.  Teri is the founder of the Global Sustainable Health Institute® and developer of The Cochrane Method®, a future-facing algorithm for decoding the human body. Teri is also one of the world’s leading experts on dietary amyloids, which is a topic I love talking about. In today’s episode, we get into what amyloids are and how they turn on viruses, cause cancer, and shorten our lives. We also explore the dangers of oxalates and histamines, plus hacks to reduce and release them. Teri and I both have our own recipes for releasing oxalates that you can try at home (they’re surprisingly simple).  We talk about how dirty poultry is killing us—and how superfoods like kale and almonds aren’t any better. We break down the benefits of regenerative farming, and share ways to make your dollar stretch if you can’t afford grass-fed meat. Plus, Teri tells us what she personally eats.  (00:02:01) The Big 4 Metabolic Impairments (00:08:21) The Dangers of Oxalates (00:12:02) The Fifth Disruptor: Histamine (00:16:22) Becoming Your Own Body Interpreter (00:28:41) How Do We Get Off Oxalates? (00:35:41) Dave’s Recipe for Releasing Oxalates (00:44:40) Hacks for Histamines (00:50:32) Amyloid 101: What You Should Know (00:56:56) Should You Beware of B6? (00:59:54) What’s the Best Kind of Protein? Sponsors Calroy Arterosil & Vascanox Bundle | Head over to calroy.com/dave for an exclusive discount. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: tericochrane.com Instagram: @tericochranebeyondnutrition YouTube: @TeriCochrane The Global Sustainable Health Institute: globalsustainablehealthinstitute.com Read: The Wildatarian Diet by Teri Cochrane  What You Eat is Turning Your Genes On and Off – Teri Cochrane – #646 The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Meet the man who’s making leaps forward in functional movement training.  Ben Patrick (aka the Knees Over Toes Guy) went from chronic knee issues to becoming a dunking sensation with his remarkable 42-inch vertical leap. His journey led him to discover the unconventional “knees over toes” method. He now trains to reverse joint pain and defy aging. In this episode, Ben shares his three game-changing foundations of exercise. We look back at the history of backward walking, and talk about its benefits today. Ben gives us his best tips for strengthening and healing knees, calves, shins, hip flexors, and shoulders. We start from the ground up with fixes for feet and toes. Plus, we talk about the problem with most shoes. Today’s biggest takeaway is recognizing the connection between functional movement and longevity. Functional training is key to how long you live and how well you live. Whether you’re 18 and want to do parkour or you’re 80 and want to get up off the floor—or still do parkour—you’ll want to hear this one.  (00:04:45) What’s Up With Knees Over Toes? (00:13:58) Strengthening Joints, Not Just Muscles (00:19:54) Starting Off on the Right Foot (00:28:21) Taking It Back to Basics (00:38:30) Will These Workouts Help or Hurt Your Joints? (00:45:09) Fixes From the Toes Up (00:53:48) How To Have Healthy Hip Flexors (01:00:33) Healthy Movement Patterns for Life (01:03:03:) Secrets To Shoulder Healing (01:05:50) Marketing That Actually Helps People Sponsors Quantum Upgrade | Go to QuantumUpgrade.io/Dave for a 7-day free trial Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: atgonlinecoaching.com ATG Equipment: atgequipment.com Instagram: @kneesovertoesguy YouTube: @TheKneesovertoesguy  TikTok: @kneesovertoesguy Biohacking Conference: biohackingconference.com The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we're learning how to Biohack like a Woman. And trust me, it's not about counting calories or giving up your favorite foods; it's a whole new paradigm. I'm thrilled to introduce you to our incredible guest today, someone I've had the privilege of working with for several years—Aggie Lal aka Biohacking Bestie.  Aggie is not your average biohacker; she's a public figure, bestselling author, health coach and a TEDx Speaker. She's been featured on TV and started the renowned Travel her Shoes blog over a decade ago, eventually leading her down the path of biohacking after realizing the toll constant travel can take on your health. Aggie's journey has led her to establish the Higher Self Academy, where she offers courses to help individuals, especially women, personalize their biohacking journeys. She's also the host of the Biohacking Bestie podcast—make sure to check out our recent conversation on her show.  I love the work Aggie’s doing so much, that I even wrote the foreword for her groundbreaking new book, Biohack Like a Woman, which is all about revolutionizing weight loss and biohacking specifically tailored for women. In today's episode, we delve into topics like fertility, understanding perimenopause, and exploring distinct biohacking recommendations for men and women. Aggie and I discuss why women must honor their cycle when trying new practices and the common challenges women face when under-eating calories and exercising. Plus, Aggie shares her valuable nutritional advice for women, including protein intake per meal.  (00:02:01) Aggie’s Mission To Empower Women Through Biohacking (00:10:46) Addressing Stress Response Capacity & The Importance of Rest & Recovery (00:21:12) Biohacking Your Cycle, Fertility & Birth Control (00:34:55) Nourishing Women: Understanding the Impact of Caloric Deficiency & Exercise (00:44:53) Embracing New Relationship Dynamics & Women’s Innate Power (00:54:24) How Biohacking Is Disrupting Mainstream Medicine (00:59:21) Nutritional Recommendations for Women Sponsors BiOptimizers Magnesium Breakthrough | Go to bioptimizers.com/dave for 10% off your order. ARMRA | Try it out for yourself at tryarmra.com. Use code DAVE to get 15% off your first order. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Read: Biohack Like a Woman  Biohacking Bestie: biohackingbestie.com Higher Self Academy: higherselfacademy.co Instagram: @aggie Instagram: @biohackingbestie YouTube: @biohackingbestie TikTok: @biohackingbestie Biohacking Bestie Podcast: biohackingbestie.com/pages/biohacking-bestie-podcast The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s very special episode comes from inside Kimbal Musk’s kitchen, where I get a hands-on look at his passion for cooking, community, and regenerative farming. Kimbal Musk is a South African restaurateur, chef, entrepreneur and a board member at Tesla Inc. and SpaceX, companies led by his brother, Elon Musk.  Outside of the tech space, Kimbal is the force behind The Kitchen Restaurant Group and co-founder and chairman of Big Green, where he's pioneering outdoor classroom Learning Gardens in schools nationwide. Additionally, Kimbal co-founded Square Roots, an innovative urban farming venture utilizing hydroponic, climate-controlled shipping containers.  In our last interview at his newly opened restaurant, The Kitchen, we explored the intersection of technology, regenerative agriculture, and grass-fed cuisine. Today, we unpack Kimbal's passion for food and community. Seriously, we’re not just chatting about technology and longevity here—Kimbal teaches me how best to prepare, serve, and enjoy grass fed steak to perfection.  During this live tutorial, we talk about how the energy you put into preparing your food really does impact how it tastes, and his unique perspective on innovation and leadership, gained from working closely with his brother Elon and the teams at Tesla and SpaceX.  Then, we explore the highlights of his new cookbook, The Kitchen Cookbook: Cooking for Your Community, a treasure trove of real-food recipes accompanied by easy to follow video tutorials. It’s an incredibly valuable resource for anyone that’s interested in bringing more realness to their food prep and diet. (00:02:14) Embracing Community Through Food (00:18:33) Teaching Kids About Regenerative Farming With Big Green (00:28:56) Try the Kitchen Cookbook for Better Family Meals (00:38:52) Kimbal Musk on Psychedelics: In or Out? (00:43:06) Cooking for Elon Musk (00:47:27) Learn How To Prep & Cook a Beautiful Grass-Fed Steak Live (00:59:22) Kitchen Thoughts on Longevity & Death (01:04:12) Exploring the Link Between Quality Fats & Testosterone Sponsors Apollo Neuro Wearable | Head to apolloneuro.com to save 15% on your Apollo wearable. CAROL Bike | Save $250 on CAROL Bike until January 15th with code DAVE at carolbike.com. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Organic Revolution: Kimbal Musk’s Mission to Take Down Big Food # 504 Big Green: biggreen.org  Read: The Kitchen Cookbook by Kimbal Musk The Kitchen: thekitchen.com Read: Elon Musk by Walter Isaacson The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is not a scientist but a true visionary. Gary Vaynerchuk (aka Gary Vee), is a self-made entrepreneur and digital marketing pioneer. He started his business journey with a lemonade stand at age seven. Now, he’s a prolific content creator, best-selling author, and the co-founder of the massive digital agency VaynerMedia.  What I love about Gary is that he leads with integrity, optimism, and, above all, gratitude. He’s a guy of wisdom, not just business—and that’s an important element of what The Human Upgrade is all about. In today’s episode, we explore how entrepreneurship has changed since Gary and I started. We get into how to grow a business in 2024 and Gary’s advice for anyone starting out. His secret to success will surprise you.  We talk a lot about gratitude, and how that lens has shaped Gary’s long career and kept him from burning out. Gary also shares his perspective on today’s social media landscape, the importance of kind candor, and why we should look to our elders.  No doubt, listening to Gary will inspire you to go after your passions and try that thing you’ve been putting off. In Gary’s words, your happiness is worth fighting for! (00:02:01) Redefining Success as an Entrepreneur (00:07:02) How Gary’s Upbringing Impacted His Success (00:10:32) The Truth About Social Media in 2024 (00:14:49) Is Everyone Just Copying Each Other? (00:18:50) Gratitude As the Antidote for Burnout (00:24:11) Championing Wisdom Instead of Youth (00:29:21) Prioritizing Joy Over Riches (00:38:02) Recognizing the Importance of Kind Candor (00:43:08) Reframing Relationships & the Perspectives You Engage With (00:47:17) Leading With Gratitude, Not Fear Sponsor 40 Years of Zen | Go to 40yearsofzen.com/dave to receive an exclusive offer for podcast listeners.  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: garyvaynerchuk.com Instagram: @garyvee TikTok: @garyvee Facebook: Gary Vaynerchuk  YouTube: @garyvee X: @garyvee Discord: VeeFriends  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I'm excited to welcome back Dr. Steven Gundry to The Human Upgrade for his sixth appearance, a tribute to his remarkable insights and ongoing research. Dr. Gundry, a true pioneer, is renowned for his books like "The Plant Paradox" and his groundbreaking work on lectins, changing how we understand our body's reaction to food. He's also a top cardiothoracic surgeon and a leader in robotic cardiac surgery, with over two decades of research into the microbiome, using diet and nutrition as key treatment tools. His book, "Unlocking the Keto Code," and his wellness line, GundryMD, have made significant impacts in health and nutrition. In this episode, we dive into cutting-edge research from his new book “Gut Check.” Dr. Gundry discusses the microbiome's connection to disease, and gut health's role in hormone regulation, crucial for mental health during menopause. He'll also share insights on dietary choices, the truth about parasites, and nicotine's unexpected role in longevity. Dr. Gundry's transformative wisdom bridges traditional and alternative medicine. A big thank you to him for another enlightening visit. Thanks for joining us on this journey of discovery! (00:00:22) The Latest Research on How To Reverse Disease (00:10:16) The Link Between Leaky Gut & Gluten (00:16:50) Debunking Blue Zones (00:19:28) What Meat Products You Should Eat & Avoid (00:23:43) The Latest Data on New 5GC, 5AC & Fermented Meat (00:34:27) The Real Issue with Oxalates & How To Boost Your Defenses (00:41:33) How the Microbiome Influences Hormones & Menopause (00:48:10) What Foods Have the Highest Risk for Parasites According to Dr. Gundry (00:55:11) Benefits & Risks of Berberine (00:58:21) The Surprising Truth About Nicotine & Longevity (01:09:11) The Downside to Too Much Olive Oil Sponsors ARMRA | Visit tryarmra.com and use the code DAVE to get 15% off your first order. Leela Q | Visit leelaq.com/dave and get a 10% discount on LeelaQ products.  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Read: Gut Check by Dr. Steven Gundry Website: drgundry.com Podcast: The Dr. Gundry Podcast Keto Gets an Upgrade – Dr. Steven Gundry #912 How to Identify Your Energy Blockers and Beat Fatigue – Dr. Steven Gundry with Dave Asprey – #803  How Foods are Harming Your Kids – Steven Gundry, M.D. – #649 Healthy Aging Begins and Ends in the Gut – Dr. Steven Gundry #604 How Nutrition Can Reverse Disease and the Impact of Lectins – Dr. Steven Gundry – #417 The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On today’s Upgrade Spotlight episode, we’re talking all about NAD+. In the biohacking world, everyone and their mother has heard of NMN and NAD+, but there’s more to it than meets the eye.  To get into the nitty gritty of NAD+, we’re joined by Dr. Gregory Kelly, a naturopathic physician and the lead product formulator at Neurohacker Collective, also known as Qualia. I’m an advisor to the company, and they do fantastic and innovative work in the longevity space. Their NAD+ supplement is a quantum leap in biohacking and a no-brainer to add to your stack.  In today’s episode, Dr. Kelly explains what NAD is and why it’s essential for longevity, cognition, energy levels, and athletic performance. We talk about the differences between NR, NMN, and Niacinamide. We also explore the most efficient way to get NAD. Is an IV worth the money or will supplements give you more bang for your buck?  Plus, Dr. Kelly breaks down exactly what’s included—and not included—in the Qualia NAD+ formula. I’ve been a major proponent of NAD for more than 10 years, but I don’t like to spend all my time and money getting it. If you feel the same, you’re going to want to tune into this episode.  (00:01:55) What Is NAD & Why Do We Care? (00:06:19) The Most Efficient Way To Get NAD (00:09:55) Sirtuin’s Superpowers  (00:14:42) The Qualia NAD+ Formula  (00:22:37) The Buzz on Coffee Berry  (00:25:53) When Is the Best Time To Take NAD+?  (00:30:01) NAD+ in Clinical Trials  (00:34:16) What’s NOT in the Qualia Supplement  (00:38:02) A Quantum Leap for Biohacking  Episode Sponsor Neurohacker | Boost YOUR NAD+ up to 50%* + GET 50% OFF  go to neurohacker.com/DAVENAD. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Visit neurohacker.com/davenad to save 50% on Qualia NAD+ by Neurohacker  Neurohacker Collective: neurohacker.com Neurohacker Collective Instagram: @neurohacker  Linkedin: Gregory Kelly  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered.  Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJets. Beyond this, he's partnered with Zico coconut water, selling it to The Coca-Cola Company, and has ventured into the music industry, co-writing Billboard Top 100 hits and co-founding Alphabet City Sports Records.  Jesse is also an acclaimed triathlete and author, with his book, Living with a Seal, becoming a New York Times bestseller. As we step into the early days of 2024, this episode is all about providing you with clear, direct methods to upgrade your life across various facets—work, fitness, and personal development. Tune in as I compare and contrast my organizational methods with Jesse's, the goal being to introduce you to strategies that resonate with you and align with your personality.  You'll gain insights into how Jesse efficiently prioritizes his calendar and the skills needed to outperform competition when you’re starting out in business. We also explore habits and tools for staying physically and mentally young, our favorite biohacks, my personal excitement in the field of longevity, and ways to structure your life for maximum return on investment, both in terms of monetary success and happiness.  While our methods differ in some areas, our objective is the same: to live a life with minimal regrets, whether you reach 80 or 180 years old. Join us as we discuss the habits of successful entrepreneurs—both from our experience and learning from others at the top of their game—and discover practical ways to implement these lessons into your life. (00:00:20) The Secret to Jesse’s Success in Business & Triathlons (00:05:10) How Jesse Organizes His Life & Implements New Habits (00:22:49) Structuring Support Systems & Early Hires (00:32:41) Lessons From Living With a Seal & Monks (00:48:19) What Biohacks Dave Is Most Excited About (00:54:21) How To Organize Your Time Efficiently (01:01:54) The Mindset & Habits of Successful Entrepreneurs (01:10:34) The Recipe for a Fulfilling Life (01:18:46) Dave’s Top Tools for Longevity Sponsor: https://www.viome.com/dave to save $150 full body intelligence test. Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: jesseitzler.com Instagram: @jesseitzler TikTok: @jesseitzler YouTube: Jesse Itzler Linkedin: Jesse Itzler The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Anthony Youn, aka “America’s Holistic Plastic Surgeon,” is an expert in your face. He joins us to answer some burning questions… Can plastic surgery actually be holistic? Can you turn back the clock without going under the knife? And… What work should I get done to my face? Today, we’re talking all about how to hack your face and save your skin.  Dr. Youn is a nationally-recognized, board-certified plastic surgeon. He’s the most followed plastic surgeon on social media and a TikTok star. He’s the author of The Age Fix, In Stitches, and Playing God. His new book, Younger For Life, is a complete holistic guide to anti-aging using a process he coined called Autojuvenation.  In today’s episode, we get into what Autojuvenation is, and how it helps you look younger without surgery—a surgeon who wants to help you avoid surgery! We talk about blending biohacking and cosmetics, natural vs. medical-grade skincare, collagen peptides, treating hair loss, and whether sunscreen causes or prevents cancer.  Dr. Youn also tells us the dumbest things that both men and women do to their faces—and how to avoid them. Let’s face it, many of us want to look younger. This conversation is a fascinating look at how to approach aesthetics from a biohacker’s perspective.  (00:01:55) Is There Such Thing As Holistic Plastic Surgery? (00:05:12) Natural vs. Medical-Grade Skincare (00:09:36) Holistic Alternatives That Traditional Physicians Don’t Know (00:16:47) Does Topical Collagen Work? (00:19:45) What Cosmetic Work Should Dave Have Done? (00:25:20) Blending Biohacking & Cosmetics (00:30:38) The Dumbest Things Men Do to Their Skin (00:35:37) Is Sunscreen Preventing or Causing Cancer? (00:38:33) The Dumbest Things Women Do to Their Skin (00:43:54) The Hair-Raising Effects of Hair Loss (00:52:35) Additional Skin Biohacks from a Pro Sponsors:Tru Kava https://trukava.com/ use code Dave15One Skin: https://www.oneskin.co/ use code Upgrade15 Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: dryoun.com Pre-order: Younger For Life (over $100 value of free bonuses) TikTok: @doctoryoun  Instagram: @tonyyounmd YouTube: @DoctorYoun Podcast: The Holistic Plastic Surgery Show   The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready for this important download on a fascinating biohacking compound you haven’t heard me talk about before: Urolithin A. It’s a postbiotic that supports the mitochondria, and it’s backed by impressive studies on longevity, anti-cancer effects, cognitive function, and muscle strength. In fact, this compound has earned a place in my permanent stack—which you know isn’t easy to pull off. Today, I chat with Dr. Dominic Denk, who’s done some of the original research on Urolithin A and the company that makes it, Timeline Nutrition powered by Mitopure. Dr. Denk works as a physician in the Department of Internal Medicine at University Hospital Frankfurt.  Dr. Denk breaks down what Urolithin A is and how it impacts aging and cancer prevention—answering questions on when, how, and why to take Mitopure—before we delve into the powers of mitochondria, how to have more energy production in your cells, and the relationship between energy production and cancer.  We also talk T cells, autoimmunity, and inflammation. Plus, we get into the differences in healthcare and pharmaceutical overreach in the U.S. and Germany. Tune in to uncover the latest life-changing compound—and find out what it will do for your heaviest lift in the gym, your cognition before your next big meeting, and to reverse aging over time.  (00:03:31) Understanding Urolithin A  (00:08:43) Genetic vs. Mitochondrial Cancer  (00:14:48) Getting to the Root of Autoimmunity  (00:21:19) Strong Evidence on Muscle Strength  (00:23:59) Does Cancer Hate Americans?  (00:27:59) Why Do We Age?  (00:31:35) The Best Studied Compound You’re Not Taking  (00:33:02) Talking T Cells  (00:36:22) Healthcare in Germany vs. The U.S.  (00:43:31) Urolithin A & Hot/Cold Therapies  (00:45:55) Tripling Down on mTOR  (00:52:05) Are There Downsides to Urolithin A?  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Timeline Nutrition: timelinenutrition.com and use code DAVE to save 10%. After January 1st, 2024, TimelineNutrition.com/dave for 30% discount. Mitopure: mitopure.com X: @DomDenkMD Linkedin: Dr.med. Dominic Denk  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity.

Energize and enliven your life by forging strong human connections for 2024 and beyond!

This episode is a deep dive into the heart of modern fitness, led by one of its most influential figures. Joining me today is Lavinia Errico, the visionary co-founder of Equinox Fitness Clubs. Lavinia isn't just a pioneer in the fitness industry, she's a passionate advocate for a life that's healthier, more fulfilled, balanced, and brimming with joy.  She's dedicated to helping others achieve these same goals, inspiring people to delve into self-awareness and embrace transformative journeys. With her belief in enjoying the journey and embracing the process, Lavinia has shaped not just her own life but the lives of countless others towards seeing, feeling, and living remarkable results. Today, you’ll hear about how Lavinia's career in fitness and biohacking began with the birth of the modern fitness movement and Equinox as she shares challenges and triumphs of starting a fitness revolution in 1980s New York. You’ll also learn about the unique ethos that set Equinox apart and how building a business with family shaped its upward trajectory. This conversation is threaded with insight into the life of an entrepreneur, the realities of being a CEO, and how Lavinia intuitively balanced her professional journey with motherhood. Lastly, you’ll get a taste of Lavinia's wellness rituals, her philosophy as a lifelong learner, and her exciting new chapter with MOVEJOY, aimed at creating a more stress-free, joyous workout experience for everyone.  (00:01:41) Laying the Foundation of Equinox (00:10:44) Finding the Joy of Movement (00:18:56) Advice for Women in Business (00:24:51) The Honest Cost of Being an Entrepreneur & CEO (00:32:14) Wellness Rituals & Being a Student of Life (00:44:47) Introducing Move Joy (00:55:27) Shifting the Why Behind Movement Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: movejoy.life Instagram: @laviniajoy LinkedIn: Lavinia Errico The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today is a long-awaited show with none other than Bryan Johnson, an entrepreneur, venture capitalist, author, and professional rejuvenation athlete on a mission to discover the next evolution of humankind. While Bryan is well known in the longevity space, I’ve been a fan of his work for years because of his neuroscience background.  Bryan started a company called Kernel, which makes devices that monitor and record brain activity. Kernel uses what I would call the most comprehensive way of looking at the human brain ever. He is the founder of OS Fund and Braintree, and he spearheads Project Blueprint, an anti-aging experiment where he’s spent multiple years and millions of dollars developing an algorithm to live longer.  In today’s wide-ranging talk, we discuss the future of optimizing our brains with AI—delving into all things biohacking and longevity while exploring complicated questions like… Can you die of loneliness? And… Are your critics making you old? Plus, we talk testosterone—an often triggering topic, but an essential conversation. Bryan shares his perspective on why he would rather be respected by people in the 25th century than understood now. Stick around for his surprising takes on olive oil, body hair, and saunas.  (00:59) Biohacking The Brain  (05:34) Are Your Critics Making You Old? (12:52) What Makes Bryan Tick (20:09) The Longevity-Loneliness Connection  (28:27) Accounting For Bio Individuality in Health Protocols  (39:09) Does Having a Partner Help You Live Longer?  (47:59) Olive Oil vs. Saturated Fats  (54:39) Talking Testosterone  (01:07:52) Expanding Consciousness with Psychedelics  (01:12:06) Questions from the Live Audience  Sponsor: Try Qualia NAD+ with an extra 15% off with code Dave15. Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: protocol.bryanjohnson.com Kernel: kernel.com Read: Don’t Die by Zero  Instagram: @bryanjohnson_  YouTube: Bryan Johnson  Linkedin: Bryan Johnson  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Coming to you live from Austin, Texas, I can’t wait for you to meet Dan Freed—a man who’s journeyed from the hot kitchen of high-end cooking to the frontier of brain improvement. Dan’s the founder and CEO of Thesis, a company that's revolutionizing the way we think about our brain's potential, and his journey is one of resilience and innovation.  Picture this… A kid struggling with focus throughout childhood, he drops out of high school and claws his way up in the ruthless restaurant industry to become a saucier in a three-star Michelin kitchen. But the real twist comes when Dan, grappling with burnout, stumbles upon cognitive performance supplements. This discovery didn't just change his mental game, it transformed his entire life.  Fast forward through degrees from Yale and INSEAD, and you have the Dan that sits down for this interview—committed to helping others harness their brainpower to the fullest. We get into the nitty gritty of nootropics and the supplement industry, talking about how Dan's fight with burnout and learning challenges led to the birth of Thesis Nootropics. We share tips on adapting human biology to our modern world, discuss the thorny issues of regulation and quality in the supplement industry, and explain how Thesis uses a unique combined approach of customizing nootropics and expert support for their customers.  We round it all off with a look at the remarkable, results-driven formulas that Thesis offers, and how focus is the key to unlocking our greatest potential. Dan's story is a living proof that sometimes, a couple of stumbles can lead to an incredible leap forward, thanks to some conscious action. That’s the kind of journey we all can learn something from. (00:02:14) How Burnout & Learning Challenges Inspired Thesis Nootropics (00:19:15) Is Using Nootropics Cheating? (00:25:37) Tips for Adapting Human Biology to the Modern World (00:32:33) How Thesis Is Customizing Nootropics (00:40:59) Tips for Supporting Your Body’s Homeostasis While Taking a Stimulant (00:46:33) Dave Rings the Alarm on Formulating With Vitamin B6 (00:50:53) Regulation & Quality Concerns in the Supplement Industry (00:57:41) Key Ingredients in Thesis’ Clarity & Logic Formulas That Drive Real Results (01:04:28) Unlocking Your Potential Through the Power of Focus Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: takethesis.com and use code “Asprey” for a 10% off all Thesis products. Instagram: @takethesis Facebook: Take Thesis The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

IF done right helps women balance hormones, improve metabolic health, lift brain fog, get more sleep and crank up physical and mental energy.

Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode. Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, Jaiya dedicates her expertise to helping people understand their unique erotic blueprints and their impact on intimate lives. Her latest book, "Your Blueprint for Pleasure," offers invaluable insights into a revolutionary language for bedroom communication and sexual vitality. This episode delves into the concept of erotic blueprints, Jaiya's research, and the unique paths to turn-on and blissful gratification for each individual. This conversation aims to understand people's true desires and needs in intimate relationships, free from taboos or judgment. Highlighting that sex and intimacy are vital for well-being, just like food and breathing, this discussion includes personal experiences and emphasizes the importance of vulnerability. Learn how understanding your erotic blueprint can enhance connections and satisfaction in the bedroom. Whether seeking to enrich intimate life or deepen understanding of human biology and connection, this episode offers valuable insights for everyone. (01:34) Reconciling Spirituality & Sexuality: Jaiya’s Sexual Empowerment Journey (12:00) Why Sex Is the New Frontier of Personal Growth & Biohacking (15:25) Jaiya’s Wildest Energetically Erotic Experience (21:35) Conscious Kink & Blending Psychedelics With Sexuality (30:52) Your Pleasure Blueprint: Defining the 5 Erotic Types (34:55) Discovering the Erotic Blueprint Through Her Own Relationship (40:01) Addressing the Intimacy Issue in Our World & Sending Love Through the Field (46:44) Confronting the Taboo of Pleasure (52:11) Mastering Energetic Sexuality & Orgasms (01:01:48) Risks in Using Psychedelics for Creation Energy (01:06:49) The Dark Side of Spiritual Ecstatic Altered States & How To Protect Your Field Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: blueprintbreakthrough.com Read: Your Blueprint For Pleasure by Jaiya  Instagram: @missjaiya The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he delves deep into topics that both he and I hold near and dear—nootropics and brain enhancement.  Jim Kwik is a widely recognized world expert in memory improvement, brain function, and accelerated learning. After a childhood brain injury left him learning-challenged, Kwik created strategies to dramatically enhance his mental performance. He has since dedicated his life to helping others unleash their true genius. In addition to being an author, he serves as ultra-informed host of the top education training podcast: Kwik Brain. His mission: No brain left behind. From overcoming childhood adversity and turning it into a superpower, to the secrets behind better memory and accelerated learning, this episode is full of tools for enhancing cognitive function. Plus, we explore the groundbreaking concepts Jim covers in Limitless: Expanded, including the use of nootropics to elevate brain function, his favorite daily biohacking techniques and brain exercises, and how identifying your brain animal can enhance your self awareness and therefore potential.  (00:01:44) Jim Kwik’s Inspiring Brain Health Journey (00:10:18) Top 5 Most Recommended Nootropics (00:16:49) Supplements for Brain Health & Longevity (00:23:32) Jim’s Biohacking Must-Haves & Daily Routine (00:29:53) Healing the Emotional Thread & Embracing Post-Traumatic Growth (00:36:03) Top Exercises for Your Brain (00:47:41) C.O.D.E. – Understanding Your Brain Animal (Cognitive Type) (00:55:57) Leveraging Self-Awareness as a Superpower Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: jimkwik.com Read: Limitless Expanded by Jim Kwik Podcast: Kwik Brain Instagram: @jimkwik YouTube: Jim Kwik LinkedIn: Jim Kwik The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats. Shaahin's story doesn't stop there. Since those days, he's become an Amazon expert, successfully selling nootropics and a variety of other products on the platform. He's also a filmmaker and author of the book, “Billion: How I Became the King of the Thrill Pill Cult.”  From Fleeing Iran at the age of five to being homeless and living out of his car, Shaahin's journey is nothing short of remarkable. It's safe to say he's one of the most interesting individuals I've had the pleasure of interviewing.  We dive into Shaahin's captivating journey, exploring his transformation from a young criminal to a thriving entrepreneur. You’ll also learn about what went into his groundbreaking herbal ecstasy formula and how he managed to get his business off the ground. Along the way, we discuss the challenges of navigating the bureaucracy of big government, the importance of seeking help when needed, and the valuable lessons Shaahin learned from building and eventually exiting his herbal ecstasy empire.  We also delve into how he managed to run a nine-figure company selling on Amazon, the mindset benefits of Brazilian jiu-jitsu training, the power of curating ideas, and how you can strategically leverage podcasts as an entrepreneur. Join us on a ride you won't want to miss. (01:47) How Shaahin Became the King of the Thrill Pill Cult (07:36) Formulating Herbal Ecstasy & Building a Million-Dollar Business (16:34) Navigating the Bureaucracy of Big Government (28:04) Pro Tip for Entrepreneurs: Why It’s Important To Ask for Help (32:09) What Cheyene Learned From Building & Exiting His Business (37:29) What To Do When You Make Your First Million (39:21) Scaling a 9-Figure Company Selling on Amazon (45:05) Lessons From Martial Arts & Our Bets on Musk vs Zuckerberg (54:03) The Tactical Advantage of Podcasting & Being a Curator of Ideas (01:03:30) Media Training 101 Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: shaahincheyenne.com PodcastCola: podcastcola.com Instagram: @shaahincheyene Podcast: Business Story of the Week LinkedIn: Shaahin Cheyene The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus.  But what's especially exciting is how John has evolved his insights to address the changing dynamics between men and women in the modern world, as he highlighted in his 2020 book, Beyond Mars and Venus: Relationship Skills for Today's Complex World. Now, why is this episode a must-listen? Well, John isn't just a relationship expert; he's also a seasoned biohacker who understands the profound impact of our environment – including relationships – on our hormones, happiness, and dopamine levels. In essence, he's been biohacking before it even had a name. With decades of wisdom, he offers invaluable insights into navigating the complexities of male-female relationships in today's world. Delve into the fundamental differences between men and women, the importance of appreciation in relationships, what truly motivates men, and practical tips on boosting testosterone and managing emotions. We also explore how men and women process feelings differently, the art of setting boundaries, and the language of love as the language of hormones. Get ready for a masterclass in understanding the dynamics of modern relationships and how to create lasting happiness. (00:59) Understanding Fundamental Differences Between Men & Women (04:38) Do Men Exist To Make Women Happy? (06:32) Exploring What Drives & Motivates Men (11:09) How To Boost Testosterone & Navigate Emotions (19:14) Why Men Disconnect When Talking About Feelings (30:22) How Men Can Help Women Come Back Into Balance (39:17) Setting Boundaries & Working on Your Relationship (49:41) Advice for Women for How To Talk About Their Feelings With Their Partner (01:02:22) Why the Language of Love Is the Language of Hormones (01:05:48) What Women Need in a Relationship (01:13:07) The Defense Against Attacks on Your Reputation (01:17:49) Techniques for Processing Emotions (01:25:32) Thoughts on Estrogen Receptor Degraders (01:31:48) What Masturbation Does to Men vs. Women (01:37:42) Advice for Couples Not Having Sex Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: marsvenus.com Read: Beyond Venus and Mars by John Gray Instagram: @johngraymarsvenus_official LinkedIn: linkedin.com/in/marsvenus The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention experiments, and examines the profound effects of healing and connection on our being. The conversation extends to the transformative power of expanding connection beyond the individual, the latest scientific developments supporting Lynne's theories, and the exciting potential of new technologies in quantum healing. The episode covers the role of intention in healing polarized communities and intriguing phenomena, such as The Simpsons' seemingly magical foresight. Get ready for a thought-provoking journey with Lynne McTaggart that promises to expand horizons, challenge beliefs, and inspire exploration into the uncharted territories of consciousness and intention. (03:01) What Is Quantum Field Therapy? (06:47) The Power of Eight (16:23) Inside the Power of Eight Experiments (19:40) How Healing & Connection Bring About States of Oneness (30:12) What Happens When You Expand the Group Beyond Eight (34:29) Evolving Our Understanding With the Latest Science (41:30) How New Modalities Support Lynne’s Findings (49:21) Lynne’s Measurement of Success: Stories of Real World Impact (56:44) Joining a Power of Eight Group or Intention Experiment (01:01:45) Healing Polarized Communities Using Altruistic Intention (01:09:14) What Technologies Can Push Boundaries Further? (01:16:15) How Did The Simpsons Magically Predict the Future? Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Website: lynnemctaggart.com Read: The Power of Eight by Lynne McTaggart YouTube: Lynne McTaggart Instagram: @lynnemctaggartofficial The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Join me for a profound conversation with Mark Nepo, one of the most spiritually influential people on earth, as we explore inner resilience, wisdom from adversity, and the fusion of science, health, and spirituality.

Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg over 25 years ago by implanting a chip in his arm, the size of a coin, enabling him to interact with the digital world in ways that were once unimaginable. But this isn't just about becoming a cyborg; it's about the potential, the risks, and the opportunities at the intersection of AI, robotics, and biomedical engineering. In doing so, we discuss the fascinating implications of merging humans with technology and how it can reshape our understanding of reality. Kevin's fearless exploration into the world of cybernetics is truly pioneering. He has been willing to take risks to expand our knowledge and possibilities as humans. Join us as we explore the profound implications of merging biology with technology, opening up new realms of human potential and perception, and what our future could hold as technology and research continues to progress.  (00:01:43) The Realities of Pioneering Human Enhancement (00:10:05) Kevin’s Implantation Experiment & Research (00:18:10) Expanding Our Biological “Software” (00:24:39) How Far Is Too Far? Risk Tolerance for the Sake of Science (00:32:47) Exploring Human Enhancement Possibilities (00:39:21) Kevin’s Take on Longevity From His Brain Cell Research (00:43:13) Biohacking as an Entry Level Point Into Cyborgs (00:52:41) The Future of Cyborgs, Humans & Artificial Intelligence Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books  Podcast: Futures Podcast  Read: I, Cyborg by Kevin Warwick  Read: Artificial Intelligence: The Basics by Kevin Warwick  Linkedin: Kevin Warwick  The Human Upgrade is produced by Crate Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Francesca LeBlanc, board certified chiropractor, a doctor of natural medicine, and a clinical nutritionist, takes us through the winding roads of food, lifestyle, and hormones in women.

Upgrade your understanding of skin longevity with Carolina Oliveira, founder of OneSkin, as she explores the profound connection between skin health and overall well-being.

Learn the finer points of power, seduction, mastery, strategy, and human nature so you can change your own patterns and upgrade your relationships.

Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician. We'll explore the theories surrounding the origins of consciousness, the incredible role of fascia in the quantum highway of our bodies, the impact of polyphenols and melanin, and the incredible new discoveries around structured water and sound frequency.

The days of a one-size-fits-all diet mentality are over. Today’s guests, Matt and Wade from BiOptimizers, are here to give us the secrets of crafting a diet tailored precisely to your genetics, goals, and lifestyle from their new book, The Ultimate Nutrition Bible.

This episode serves as the ultimate Colostrum 101 course for anyone interested in learning more, living healthier, and even for those still harboring doubts over things like fasting and ethical sourcing. Dr. Sarah Rahal answers it all and more.

Vani Hari, aka Food Babe, joins the show to talk about how to help kids make healthier food choices with insight from how her own family navigates the challenges of living in a world filled with overly processed, unhealthy food options from her new book, Food Babe Family.

Hear how I recently took up to 9 years off my biological age with the assistance of Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan joins us to explore the remarkable advancements in longevity and chronic pain treatment leveraging this new technology.

Dr. Gabrielle Lyon joins us to flex her intellectual muscles on healthy protein intake, reframing the hallmarks of aging, unlocking longevity through diet, and more. She's looking at aging in exciting new ways in her book, Forever Strong, which is packed with science-based strategies for aging well.

Science gains new ground diving into the immense benefits of cold-water swimming, immersion and plunges.

Dr. Toni Galardi, a holistic psychotherapist and author of BreastQuake, provides her research on alternative breast cancer treatments, how to lower your risk, and harnessing the healing potential of consciousness in the body.

In this episode with Rollin McCraty from the HeartMath Institute, we dive into the intersection of emotion, energetics, and technology, harnessing the power of heart rate variability for longevity and biohacking, and how our magnetic environment influences our biology and consciousness.

Fitness legend Tony Horton joins me for a conversation about his new fitness program optimized for women’s hormones, his secrets to vitality and longevity, and a deep dive into how to cultivate more resilience, adaptivity, and happiness for a more fulfilling life.

Today, we delve into the health of our skin with Rachel Varga, a double board-certified aesthetic nurse specialist, discussing how to reduce oxidative stress and implement purification and detoxification techniques to become radiant from the inside out.

In this conversation with the esteemed Dr. Gad Saad, a professor of marketing at Concordia University and author of The Saad Truth About Happiness, we explore living the life you truly desire, the role of anti-fragility in happiness, and the biological differences in male and female behaviors.

Chris Masterjohn delves into the health impacts of veganism, his latest self-experimentation with genetics with mitochondrial health, insights on trauma and energy metabolism, and the potential risks of methylene blue—underscoring the importance of correct dosage.

If you struggle with straying focus or have been diagnosed with ADHD, you won’t want to miss this one. We talk about an out-of-the-box solution to attention training with Dr. Adam Gazzaley to learn about a game called Endeavor Rx, the world's first FDA-approved video game treatment.

Hannah Kleinfeld, gut health expert and COO of Allergosan USA, joins me to discuss the importance of gut health as a foundation for wellbeing and how to optimize your supplement routine with OMNi-BiOTiC probiotics.

Intimacy expert, Susan Bratton, co-founder and CEO of two companies serving the direct-to-consumer intimate wellness space, discusses the science of sexual biohacking, how to prevent atrophy, enhance your pleasure potential, and the profound link between intimacy and longevity.

Dr. Brandon Crawford, a globally renowned neurologist from the NeuroSolution Center of Austin, is revolutionizing brain health and healing through advanced light therapies. We explore the power of light in brain function, and strategies for those facing neurological and mental health challenges.

In this conversation with Ivor Cummins, a Dublin-based biochemical engineer, we confront—head on—the antiquated systems that keep our society sick while examining the nexus of insulin resistance, heart health, and the current medical structure’s failure to diagnose and treat metabolic diseases.

America's favorite veterinarian, Dr. Gary Richter, shares all you need to know about biohacking your pet from his latest books, Longevity for Dogs and Longevity for Cats. You’ll learn which foods and supplements are best and about genetic testing that leads to a longer, healthier life for your pet.

Sleep is one of the most overlooked biohacks. Jack Dell’Accio, the CEO of Essentia, shares data on how sleeping on an organic Essentia mattress can improve REM and deep sleep by between 20 and 60 percent—therefore improving performance, longevity, and quality of life.

Today, we talk about toxins that are overlooked in your house and what you can do about them with our guest Ryan Blaser, the founder and CEO of Test My Home, an environmental company dedicated to improving your health by changing the environments you spend the most time in.

Alan Graves is the CEO of Do Not Age, a UK-based longevity company, and he’s been fully immersed in the biohacking space since 2019. In that short time, he’s become a leader in supplementation and expanded his curiosities – even as far as outer space.

Today, we hear from global inventor and investor, Saba Yussouf, about how to position STEM technologies – science, technology, engineering, and math – to prevent infection, treat water, and even fight climate change.

Forget shortcuts. How to focus on fitness, nutrition, structure and balance in equal measure.

Dr. Caroline Leaf shares how we can help kids clean up their mental mess and be more resilient—all based on research from her latest book, How to Help Your Child Clean Up Their Mental Mess. We discuss tools from the Neurocycle for self-regulation and forming better habits.

Put in the work to really know, save and complete yourself so you can love fully in the present—no perfection necessary.

In today’s episode Dr. Spar is sharing the vast range of benefits of Calroy Health Sciences products I use in my morning routine, Arterosil and Vascanox. We talk about the science behind these products, and how they help support athletic performance and recovery, cardiovascular health and even sexual function.

If you're looking at what could be holding you back in your weight loss journey, tune in to hear the advice I gave Upgrade Collective member, Nadya, about where she could be going wrong, and what to do to help her feel her best.

Our guest today is a legendary thinker, author, and philosopher. Ken Wilber has spent decades understanding how humans are all interconnected with each other, decoding through dozens of beautifully written books how we fit into the greater, massive, picture that is the expanding universe.

Learn how you can skip the surgery and create more spine fluidity with a new healing method based in regenerative medicine.

Learn how to turn your mind’s negative inner chatter into constructive self-talk with science-backed tools.

We talk to Steve Revelli about the history and bright future of using silver nanoparticles as a biohacking silver bullet. Steve's background is in science and education, now serving as the QA Manager at American Biotech Labs, home of Silver Biotics—a long-time resident of my own medicine cabinet.

Andrea Bemis is an expert in sustainable organic farming, the creator of the farm-to-table blog "Let Them Eat Dirt,” and a passionate advocate for nurturing healthy babies and children. In this episode she shares recipes and insights into creating a healthy, nourishing food environment for children.

Serial entrepreneur and conscious innovator, Naveen Jain, is out to make the world a healthier place through the use of AI-powered human data analytics. He chats about the critically important oral microbiome—and from a wider perspective—how and why the human body gets sick.

Karma isn’t a system of rewards or punishments, it’s an internal process of your own identity, intention and choices.

IN THIS EPISODE OF THE HUMAN UPGRADE™... “Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that.  He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness. “I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.” What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals. Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem. You may be one or a combination of these five primary brain types: (take this brain assessment to find out yours) Balanced: you have a very healthy brain Spontaneous: you have low dopamine Persistent: you’re often worried, rigid, and inflexible Sensitive: you need other people and isolation is hard Cautious: your GABA levels are low Learn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, "You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type.” “Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.”   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Understand mold, mycotoxins, and even bacterial toxins that exist in your homes, what's there, even down to the genetic level, and what it's doing to you.

Discover the captivating realm where biohacking, space exploration, and the significance of microbiome health in Mars-like environments converge, as Vera Mulyani, co-founder of Astrobiome and Mars City Design, shares insights on designing the Martian environment to control human biology and introduces the revolutionary microbiome product, Astrobiome.

Join Dave at the 9th Annual Biohacking conference in Orlando as he tackles the vegan vs. animal protein debate with Max Lugavere and Dr. Amy Shah, discussing health, ethics, and environmental concerns while advocating for a balanced approach to protein and exploring topics like cardiovascular health, muscle building, fasting, and the role of carbohydrates.